15 September 2025 : Clinical Research
Optimizing Ventilation Strategies to Reduce Pulmonary Complications in Frail Patients: A Comparative Study
Yang Cao AEG 1,2, Enci Liu CD 3, Yongling Xu AD 1, Changzheng Shangguan F 4, Mengxia Ge B 1, Changzheng Yuan AB 1, Baohui Xia A 1, Bo Zhang D 1, Di Gao B 1, Wangning Shangguan AE 2*, Juan Chen E 5DOI: 10.12659/MSM.948977
Med Sci Monit 2025; 31:e948977
Figure 1 Comparison of dynamic lung compliance (Cdyn) at 3 time points between individualized and standard ventilation groupsDynamic lung compliance (Cdyn) was measured at T0 (immediately after intubation), T1 (after 60 minutes of positive end-expiratory pressure [PEEP] titration), and T2 (at the end of surgery). Data are presented as mean±standard deviation. The individualized ventilation group (ΔP group) showed a consistent improvement in Cdyn compared to the standard PEEP ventilation group (N group). Cdyn – dynamic lung compliance; PEEP – positive end-expiratory pressure; ΔP group – driving pressure-guided individualized PEEP group; N group – standard PEEP ventilation group. The figure was generated using GraphPad Prism 9 (GraphPad Software Inc., USA).