03 December 2025 : Clinical Research
Biologically Guided Gamma Knife Dose Painting for Recurrent High-Grade Gliomas: A Retrospective Study Using Functional MRI Techniques
Mehmet Hakan Seyithanoğlu
ABCDEFG 1*, İsmail Yurtsever ABCD 2, Meliha Gundag Papaker DEF 1, Ahmet Serdar Mutluer CDEF 3, Tolga Turan Dundar DEF 4,5, Serkan Kitis ABCEF 1, Kerime Akdur BEF 6, Alpaslan Mayadağlı AEF 6,7
DOI: 10.12659/MSM.949489
Med Sci Monit 2025; 31:e949489
Figure 6 Axial contrast-enhanced T1-weighted MRI before and approximately 3 months after Gamma Knife treatment(A) Baseline (pre-treatment) scan shows an irregularly enhancing temporal-lobe mass consistent with recurrent high-grade glioma. (B) Approximately 3-month post-treatment scan demonstrates decreased size and intensity of enhancement, compatible with radiographic response after dose-painted Gamma Knife stereotactic radiosurgery.