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24 November 2025 : Clinical Research  

Perforin Expression and Natural Killer-Cell Proportion as Biomarkers in Secondary Hemophagocytic Lymphohistiocytosis

Jujuan Wang EF 1, Xin Li BE 2, Limin Duan BC 1, Guangli Yin CG 1, Xin Gao AF 1, Hongxia Qiu G 1, Ji Xu AD 1*, Tian Tian ORCID logo AB 1

DOI: 10.12659/MSM.950615

Med Sci Monit 2025; 31:e950615

Figure 1 Kaplan-Meier analysis of overall survival in patients with secondary hemophagocytic lymphohistiocytosis (sHLH). The survival curve illustrates the probability of overall survival over time for the entire cohort of 19 patients diagnosed with sHLH. The y-axis represents the survival probability, and the x-axis represents time in months. The median overall survival for the cohort was 17.1 months. Figure created with GraphPad Prism v8.0.

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Medical Science Monitor eISSN: 1643-3750
Medical Science Monitor eISSN: 1643-3750