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26 November 2025 : Database Analysis  

Long-Term Outcomes of Anticoagulation Monotherapy Versus Combination Therapy in Atrial Fibrillation Patients with Complex Coronary Artery Disease

Wei-Chieh Lee ABCDG 1,2*, Wei-Ting Chang F 1,2, Chon-Seng Hong B 2, Chih-Hsien Lin B 2, Chun-Yen Chiang ORCID logo B 2, Pei-Chieh Huang B 2, Zhih-Cherng Chen BF 1,2, Jhih-Yuan Shih B 1,2, Hsiu-Yu Fang EF 3,4

DOI: 10.12659/MSM.950655

Med Sci Monit 2025; 31:e950655

Figure 3 Subgroup analysis of revascularization incidence by clinical and anatomical characteristicsFigure illustrates revascularization incidence across clinical and anatomical subgroups. In the comparison of subgroups with SYNTAX score <33 (group 1 vs group 2, 16.7% vs 52.6%, P=0.021), no left main disease (group 1 vs group 2, 16.7% vs 50.0%, P=0.041), HAS-BLED score ≥3 (group 1 vs group 2, 0% vs 66.7%, P=0.021), and ACS (group 1 vs group 2, 5.0% vs 66.7%, P<0.001), significant higher incidences presented in group 2. In the comparison of subgroups with SYNTAX score ≥33 (group 1 vs group 2, 0% vs 40.0%, P=0.128), left main disease (group 1 vs group 2, 0% vs 50.0%, P=0.055), HAS-BLED score <3 (group 1 vs group 2, 16.0% vs 44.4%, P=0.082), and stable angina (group 1 vs group 2, 25.0% vs 33.3%, P=1.000), did not differ between the 2 groups.

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Medical Science Monitor eISSN: 1643-3750
Medical Science Monitor eISSN: 1643-3750