06 December 2025 : Clinical Research
Differences in Prefrontal Cortex Activation Between Predominantly Positive and Negative Symptom Profiles in Schizophrenia: A Functional Near-Infrared Spectroscopy Study
Yudiao Liang CD 1, Heping Jiang BCE 1, Bo Liu AE 1, Jie Liao B 1, Yanping Feng B 1, Ruini He AF 1, Sha Zhang BF 1, Youguo Tan AG 1*DOI: 10.12659/MSM.950780
Med Sci Monit 2025; 31:e950780
Figure 2 Illustration of the hemodynamic responses in different region-of-interest regions during the verbal fluency task in patients with predominantly positive symptoms of schizophrenia (PSZ) and those with predominantly negative symptoms of schizophrenia (NSZ). The brain regions analyzed include the left and right inferior frontal gyrus (IFG-L and IFG-R), middle frontal gyrus (MFG-L and MFG-R), and superior frontal gyrus (SFG-L and SFG-R). The graphs show the mean concentrations of oxygenated hemoglobin (HbO) and deoxyhemoglobin (HbR) over time.