02 December 2025 : Clinical Research
Comprehensive Plasma Oxylipin Profiling Reveals a Pro-Inflammatory Eicosanoid Signature and Diagnostic Biomarker Panel in Dilated Cardiomyopathy
Jia Wang
ABCDEF 1, Xue-qin Bai ABCDEF 1, Meng Li BCDEF 2,3, Xing-jie Wang BCF 4, Shuo-wen Sun BCF 4, Lei Huang ABCDEFG 3,5, Xu Zhang ACDEF 6,7*, Xin Chen ACDEF 1,8
DOI: 10.12659/MSM.950838
Med Sci Monit 2025; 31:e950838
Figure 1 Heatmap of plasma oxylipin profiles in patients with DCM versus healthy controls. Normalized intensities of 73 oxylipins (rows) across individual plasma samples (columns) from 30 patients with DCM and 30 matched healthy controls are displayed. Hierarchical clustering (Euclidean distance, complete linkage) segregates disease and control groups. Figure generated using MetaboAnalyst 6.0 (Xia Lab, McGill University, Canada). DCM, dilated cardiomyopathy.