The Silent Face of Chronic Hepatitis B: Biopsy-Supported Fibrosis Detection and the Reliability of Non-Invasive Scores (FIB-4, APRI) in Inactive, Gray Zone, and Immune-Tolerant Cases

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doi:10.12659/MSM.951084

14 December 2025 : Clinical Research

The Silent Face of Chronic Hepatitis B: Biopsy-Supported Fibrosis Detection and the Reliability of Non-Invasive Scores (FIB-4, APRI) in Inactive, Gray Zone, and Immune-Tolerant Cases

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DOI: 10.12659/MSM.951084

Med Sci Monit 2025; 31:e951084

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Figure 1 FIB-4 vs APRI ROC Curve. APRI – Aspartate Aminotransferase-to-Platelet Ratio Index; FIB-4 – Fibrosis-4 Index; ROC – receiver operating characteristic.

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The Silent Face of Chronic Hepatitis B: Biopsy-Supported Fibrosis Detection and the Reliability of Non-Invasive Scores (FIB-4, APRI) in Inactive, Gray Zone, and Immune-Tolerant Cases

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