30 January 2026 : Review article
Musculoskeletal Ultrasound and MRI in the Evaluation of Chemotherapy-Induced Peripheral Neuropathy: A Review
Yuxia Zuo BCE 1, Xingchao Xu BC 2, Cai Wu E 2, Xue Cui CE 2, Xiangqi Li A 2*DOI: 10.12659/MSM.951283
Med Sci Monit 2026; 32:e951283
Introduction
Pathogenesis of Chemotherapy-Induced Neuropathy
MSUS Technical Principles and Equipment Selection
Characteristic MSUS Manifestations of CIPN
Quantitative Assessment Parameters of MSUS
Advantages and Limitations of MSUS
Core Technical Principles of MRI (DTI/DKI)
The Correlation Between MRI Features, CIPN Pathology, and Clinical Scales
Quantitative Assessment Parameters of MRI
Limitations and Reproducibility Challenges of MRI
Standardized Protocol for Peripheral Nervous System Examination
Future Directions
Conclusions
References
Figure 1 (A) Longitudinal and (B) transverse views of a normal peripheral nerve. (C, D) Nerve enlargement with hypoechoic fascicles and disrupted architecture, consistent with peripheral nerve injury.