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15 April 2026 : Clinical Research  

Phospho-Histone H3 as a Tool for Improved Mitotic Counting and Risk Assessment in Gastrointestinal Stromal Tumors: A Study of 241 Cases

Xu Liu ORCID logo ADE 1,2, Jiao Liu BC 3, Yahui Cui CF 4, Hanhan Lei CD 1,2, Yuchang Hu DG 1,2, Yufei Liu DG 1,2*

DOI: 10.12659/MSM.952182

Med Sci Monit 2026; 32:e952182

Figure 1 The mitotic figures under hematoxylin-eosin staining in a gastrointestinal stromal tumor. (A) Ring-shaped mitotic figure, with deeply stained nuclei. (B) Fragmentary mitotic figure, with disappearance of nuclear membranes. (C) Centipede-like mitotic figure, with obvious irregularities around the nucleus. (D) Butterfly-shaped mitotic figure, with obvious irregularities around the nucleus. (E) Dumbbell-like mitotic figure, with disappearance of nuclear membranes. (F) Hippocampal-shaped mitotic figure, with disappearance of nuclear membranes.

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Medical Science Monitor eISSN: 1643-3750
Medical Science Monitor eISSN: 1643-3750