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15 April 2026 : Clinical Research  

Phospho-Histone H3 as a Tool for Improved Mitotic Counting and Risk Assessment in Gastrointestinal Stromal Tumors: A Study of 241 Cases

Xu Liu ORCID logo ADE 1,2, Jiao Liu BC 3, Yahui Cui CF 4, Hanhan Lei CD 1,2, Yuchang Hu DG 1,2, Yufei Liu DG 1,2*

DOI: 10.12659/MSM.952182

Med Sci Monit 2026; 32:e952182

Figure 3 Phospho-histone H3 immunohistochemical staining of mitotic figures. The background is clean, and the nuclear staining is clear, ranging from dark brown to black. (A) The shape is similar to that of a durian fruit, with distinct spiky-like edges. (B) The shape is similar to a crescent, with distinct spiky-like edges. (C) The shape is similar to that of a seahorse, with irregular edges. (D) The shape is similar to a crescent, with irregular edges. (E) The shape is similar to that of a centipede, with irregular edges. (F) It is in the form of fragmented nuclei, with irregular edges.

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Medical Science Monitor eISSN: 1643-3750
Medical Science Monitor eISSN: 1643-3750