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15 April 2026 : Clinical Research  

Phospho-Histone H3 as a Tool for Improved Mitotic Counting and Risk Assessment in Gastrointestinal Stromal Tumors: A Study of 241 Cases

Xu Liu ORCID logo ADE 1,2, Jiao Liu BC 3, Yahui Cui CF 4, Hanhan Lei CD 1,2, Yuchang Hu DG 1,2, Yufei Liu DG 1,2*

DOI: 10.12659/MSM.952182

Med Sci Monit 2026; 32:e952182

Figure 4 Non-specific staining of phospho-histone H3 immunohistochemistry. (A) Granularly stained cell nucleus, incomplete nuclear staining. (B) Weak nuclear staining. (C) Stained cells in the necrotic area. (D) Point-focal nuclear staining, incomplete nuclear staining. (E) Vascular endothelial cell staining. (F) Lymphocyte staining. (G) Weak staining of the cytoplasm. (H) Arc-shaped impurity, with a mitotic figure visible around it. (I) Cell staining within the vascular lumen.

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Medical Science Monitor eISSN: 1643-3750
Medical Science Monitor eISSN: 1643-3750