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22 June 2026 : Clinical Research  

Development and Validation of Machine-Learning-Based Prediction Models for Thyroid Diseases During Pregnancy

Guang Yang BCDEF 1, Yi Gao BCEF 1, Pengfei Liu BC 1, Jingwen Jiang BC 1, Hui Qiao ADEG 1*, Weixuan Sheng ORCID logo ACDE 1

DOI: 10.12659/MSM.953235

Med Sci Monit 2026; 32:e953235

Figure 2 Candidate variable screening diagram based on BorutaThe figure illustrates the results of feature selection using the Boruta algorithm. Feature variables are displayed along the x-axis, and their importance scores are shown on the y-axis. Green boxes represent features confirmed as important (“Confirmed”); red boxes denote features rejected as unimportant (“Rejected”); and blue boxes indicate the minimum, median, and maximum importance of random shadow features used for comparison (“Shadow”). Abbreviations: AID, autoimmune disease; APCD, adverse pregnancy and childbirth history; CVD, cardiovascular disease; GDM, gestational diabetes mellitus; HDP, hypertensive disorders of pregnancy; IVF-ET, in vitro fertilization and embryo transfer; PM, primipara or multipara.

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Medical Science Monitor eISSN: 1643-3750
Medical Science Monitor eISSN: 1643-3750