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02 January 2014 : Original article  

Distal Pancreatectomy with en Bloc Celiac Axis Resection for Pancreatic Body-Tail Cancer: Is it Justified?

Yan-Ming ZhouBC, Xiao-Feng ZhangDE, Xiu-Dong LiF, Xiao-Bin LiuG, Lu-Peng WuF, Bin LiA

DOI: 10.12659/MSM.889847

Med Sci Monit 2014; 20:1-5

Abstract

BACKGROUND: The aim of this study was to evaluate the safety and efficacy of distal pancreatectomy with en bloc celiac axis resection (DP-CAR) for pancreatic body-tail cancer.

MATERIAL AND METHODS: The medical records of 12 patients who underwent DP-CAR for pancreatic body-tail cancer were retrospectively studied, together with a literature review of studies including at least 3 cases of DP-CAR.

RESULTS: There were no deaths among our 12 cases. Postoperative morbidity developed in 9 cases and was successfully managed by non-surgical treatment. No patients developed ischemic complications. Median overall survival was 10 months. A total of 19 studies involving 203 patients who underwent DP-CAR were included in the literature review. The overall morbidity and mortality rates were 50.2% and 3.0%, respectively. The overall median survival after surgery ranged from 9.3 to 26 months.

CONCLUSIONS: DP-CAR is a safe and effective treatment for patients with locally advanced pancreatic body-tail cancer.

Keywords: Celiac Artery - surgery, Pancreatectomy - methods, Pancreatic Neoplasms - surgery, Survival Rate

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Medical Science Monitor eISSN: 1643-3750
Medical Science Monitor eISSN: 1643-3750