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30 August 2014 : Original article  

Efficacy of Surgical Resection for Pulmonary Metastases from Hepatocellular Carcinoma

Yan-Ming ZhouB, Xiao-Feng ZhangC, Feng YuD, Xiao-Bin LiuE, Lu-Peng WuF, Bin LiG, Jia-Mei YangA

DOI: 10.12659/MSM.890853

Med Sci Monit 2014; 20:1544-1549


BACKGROUND: The lung is one of the most common sites for extrahepatic metastasis from hepatocellular carcinoma (HCC). This study aimed to assess the efficacy of surgical resection for pulmonary metastases from HCC.

MATERIAL AND METHODS: The medical records of 9 patients who underwent pulmonary metastasectomy from HCC at 2 institutions were retrospectively studied, together with a review of studies reporting the outcomes of at least 5 patients in the Chinese and English languages.

RESULTS: There were no perioperative deaths or major complications. The 1-, 3-, and 5-year overall survival rate after surgery was 100%, 44.4%, and 33.3%, respectively. A total of 19 studies involving 443 patients who underwent pulmonary metastasectomy for metastasis of HCC were included in the literature review. The median mortality rate was 0% (range, 0–7.1%). The median survival ranged from 10.7 to 77 (median=33.2) months, and the 5-year overall survival rate ranged from 11.5% to 75% (median=36%).

CONCLUSIONS: Surgical resection is a safe and effective treatment in selected patients with pulmonary metastases from HCC.

Keywords: Disease-Free Survival, Liver Neoplasms - pathology, Lung Neoplasms - surgery

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01 November 2023 : Editorial  

Editorial: Factors Driving New Variants of SARS-CoV-2, Immune Escape, and Resistance to Antiviral Treatments as the End of the COVID-19 Pandemic is Declared

Dinah V. Parums
Science Editor, Medical Science Monitor, International Scientific Information, Inc., Melville,

DOI: 10.12659/MSM.942960

Med Sci Monit 2023; 29:e942960


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Medical Science Monitor eISSN: 1643-3750
Medical Science Monitor eISSN: 1643-3750