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15 September 2020 : Laboratory Research

Interleukin 37 (IL-37) Reduces High Glucose-Induced Inflammation, Oxidative Stress, and Apoptosis of Podocytes by Inhibiting the STAT3–Cyclophilin A (CypA) Signaling Pathway

DOI: 10.12659/MSM.922979

Med Sci Monit 2020; 26:e922979

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19 May 2022 : Animal Research

Anti-Inflammatory and Anti-Oxidative Effects of Isorhamnetin for Protection Against Lung Injury in a Rat Model of Heatstroke in a Dry-Heat Environment

Xiang Dong, Jia-Jia Li [...]

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22 Aug 2022 : Review article

Programmed Cell Death in Diabetic Nephropathy: A Review of Apoptosis, Autophagy, and Necroptosis

Nour S. Erekat,

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24 Dec 2021 : Animal Research

Lotus Seedpod Proanthocyanidins Protect Against Light-Induced Retinal Damage via Antioxidative Stress, Anti-Apoptosis, and Neuroprotective Effects

Jianmei Wang ORCID logo, Tao Yu [...]

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07 Dec 2021 : Animal Research

Tissue-Protective Effect of Erdosteine on Multiple-Organ Injuries Induced by Fine Particulate Matter

Lei Cao, Fen Ping [...]

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Med Sci Monit 2021; 27:e930909

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29 Feb 2020 : Animal Research

Dihydrotanshinone I Alleviates Spinal Cord Injury via Suppressing Inflammatory Response, Oxidative Stress and Apoptosis in Rats

Liuqian Yu, Jinfeng Qian

DOI: 10.12659/MSM.920738

Med Sci Monit 2020; 26:e920738

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25 May 2020 : Animal Research

Roflumilast, a Phosphodiesterases-4 (PDE4) Inhibitor, Alleviates Sepsis‑induced Acute Kidney Injury

Xingkai Xu, Lulei Liao [...]

DOI: 10.12659/MSM.921319

Med Sci Monit 2020; 26:e921319

2362 27 71

24 May 2020 : Laboratory Research

Long Non-Coding RNA (LncRNA)-ATB Promotes Inflammation, Cell Apoptosis and Senescence in Transforming Growth Factor-β1 (TGF-β1) Induced Human Kidney 2 (HK-2) Cells via TGFβ/SMAD2/3 Signaling Pathway

Han Sun, Cong Ke [...]

DOI: 10.12659/MSM.922029

Med Sci Monit 2020; 26:e922029

2034 44 64

31 Mar 2020 : Animal Research

Ibudilast, a Phosphodiesterase-4 Inhibitor, Ameliorates Acute Respiratory Distress Syndrome in Neonatal Mice by Alleviating Inflammation and Apoptosis

Dongjie Yang, Yihan Yang [...]

DOI: 10.12659/MSM.922281

Med Sci Monit 2020; 26:e922281

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25 Aug 2020 : Clinical Research

Dioscin Attenuates Interleukin 1β (IL-1β)-Induced Catabolism and Apoptosis via Modulating the Toll-Like Receptor 4 (TLR4)/Nuclear Factor kappa B (NF-κB) Signaling in Human Nucleus Pulposus Cells

Longhui Wang, Yuntao Gu [...]

DOI: 10.12659/MSM.923386

Med Sci Monit 2020; 26:e923386

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24 May 2020 : Animal Research

Inhibition of the Peroxisome Proliferator-Activated Receptor gamma Coactivator 1-alpha (PGC-1α)/Sirtuin 3 (SIRT3) Pathway Aggravates Oxidative Stress After Experimental Subarachnoid Hemorrhage

Ke Zhang, Hongwei Cheng [...]

DOI: 10.12659/MSM.923688

Med Sci Monit 2020; 26:e923688

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03 Feb 2020 : Laboratory Research

Inhibition of NADPH Oxidase 5 (NOX5) Suppresses High Glucose-Induced Oxidative Stress, Inflammation and Extracellular Matrix Accumulation in Human Glomerular Mesangial Cells

Yingxin Li, Yarong Li [...]

DOI: 10.12659/MSM.919399

Med Sci Monit 2020; 26:e919399

1627 25 30

27 Jun 2020 : Animal Research

Pyrroloquinoline Quinone Inhibits Oxidative Stress in Rats with Diabetic Nephropathy

Min Zhang, Jiangzhao Zhang [...]

DOI: 10.12659/MSM.924372

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04 Oct 2020 : Animal Research

Z-Ligustilide Ameliorates Diabetic Rat Retinal Dysfunction Through Anti-Apoptosis and an Antioxidation Pathway

Bing Yang, Guobin Ma [...]

DOI: 10.12659/MSM.925087

Med Sci Monit 2020; 26:e925087

3234 37 51

03 Dec 2020 : Animal Research

Peroxiredoxin2 (Prdx2) Reduces Oxidative Stress and Apoptosis of Myocardial Cells Induced by Acute Myocardial Infarction by Inhibiting the TLR4/Nuclear Factor kappa B (NF-κB) Signaling Pathway

Hangshun Li, Haina Yang [...]

DOI: 10.12659/MSM.926281

Med Sci Monit 2020; 26:e926281

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23 Jan 2020 : Animal Research

The Lipoxin A4 Receptor Agonist BML-111 Alleviates Inflammatory Injury and Oxidative Stress in Spinal Cord Injury

Jian Liu, Lei Peng [...]

DOI: 10.12659/MSM.919883

Med Sci Monit 2020; 26:e919883

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07 Jul 2020 : Animal Research

Baicalin Suppresses Bilirubin-Induced Apoptosis and Inflammation by Regulating p38 Mitogen-Activated Protein Kinases (MAPK) Signaling in Neonatal Neurons

Shuang Shi, Qianwei Cui [...]

DOI: 10.12659/MSM.926441

Med Sci Monit 2020; 26:e926441

2050 14 56

12 Jan 2020 : Animal Research

Protective Effects of Hydrogen-Rich Water Against Cartilage Damage in a Rat Model of Osteoarthritis by Inhibiting Oxidative Stress, Matrix Catabolism, and Apoptosis

ShaoWen Cheng, Lei Peng [...]

DOI: 10.12659/MSM.920211

Med Sci Monit 2020; 26:e920211

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14 Mar 2020 : Animal Research

MicroRNA-143 Increases Oxidative Stress and Myocardial Cell Apoptosis in a Mouse Model of Doxorubicin-Induced Cardiac Toxicity

Xin-Qiang Li, Ya-Kui Liu [...]

DOI: 10.12659/MSM.920394

Med Sci Monit 2020; 26:e920394

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27 Feb 2020 : Laboratory Research

Curcumin Suppresses Apoptosis and Inflammation in Hypoxia/Reperfusion-Exposed Neurons via Wnt Signaling Pathway

Jiaxing Zhou, Naisheng Wu [...]

DOI: 10.12659/MSM.920445

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21 May 2020 : Laboratory Research

ZJ01, a Small Molecule Inhibitor of the Kelch-Like ECH-Associated Protein 1-Nuclear Factor Erythroid 2-Related Factor 2 (Keap1-Nrf2) Protein-Protein Interaction, Reduces Hyperoxic Acute Lung Injury in a Mouse Model

Jun Wan, Shaoyan Lin [...]

DOI: 10.12659/MSM.920467

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18 Mar 2020 : Animal Research

The Effects of Inhibition of MicroRNA-375 in a Mouse Model of Doxorubicin-Induced Cardiac Toxicity

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26 Apr 2019 : Original article

Mesenchymal Stem Cells Reverse Diabetic Nephropathy Disease via Lipoxin A4 by Targeting Transforming Growth Factor β (TGF-β)/smad Pathway and Pro-Inflammatory Cytokines

Yihua Bai, Jiaping Wang [...]

DOI: 10.12659/MSM.914860

Med Sci Monit 2019; 25:3069-3076

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16 Jul 2019 : Laboratory Research

Apigenin Protects Against Renal Tubular Epithelial Cell Injury and Oxidative Stress by High Glucose via Regulation of NF-E2-Related Factor 2 (Nrf2) Pathway

Jichen Zhang, Xuemei Zhao [...]

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Med Sci Monit 2019; 25:5280-5288

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04 Mar 2019 : Animal Research

Calycosin Ameliorates Diabetes-Induced Renal Inflammation via the NF-κB Pathway In Vitro and In Vivo

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15 Jan 2019 : Animal Research

Chlorogenic Acid Exerts Beneficial Effects in 6-Hydroxydopamine-Induced Neurotoxicity by Inhibition of Endoplasmic Reticulum Stress

Shihai Shan, Lina Tian [...]

DOI: 10.12659/MSM.911166

Med Sci Monit 2019; 25:453-459

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30 Oct 2019 : Laboratory Research

miR-34b Alleviates High Glucose-Induced Inflammation and Apoptosis in Human HK-2 Cells via IL-6R/JAK2/STAT3 Signaling Pathway

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15 Feb 2019 : Laboratory Research

Resveratrol Reduces Oxidative Stress and Apoptosis in Podocytes via Sir2-Related Enzymes, Sirtuins1 (SIRT1)/Peroxisome Proliferator-Activated Receptor γ Co-Activator 1α (PGC-1α) Axis

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Med Sci Monit 2019; 25:1220-1231

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31 Oct 2019 : Animal Research

Maresin-1 Inhibits Oxidative Stress and Inflammation and Promotes Apoptosis in a Mouse Model of Caerulein-Induced Acute Pancreatitis

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DOI: 10.12659/MSM.917380

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20 Nov 2019 : Laboratory Research

Zafirlukast, a Cysteinyl Leukotriene Receptor 1 Antagonist, Reduces the Effect of Advanced Glycation End-Products in Rat Renal Mesangial Cells In Vitro

Liping Yan, Ani Sun [...]

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03 Aug 2019 : Laboratory Research

The Neuroprotective Effect of Steroid Receptor Coactivator-Interacting Protein (SIP) in Astrocyte Model of 1-Methyl-4-Phenylpyridinium (MPP⁺)-Induced Parkinson’s Disease

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DOI: 10.12659/MSM.912106

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13 Dec 2019 : Laboratory Research

Salvianolic Acid C Attenuates LPS-Induced Inflammation and Apoptosis in Human Periodontal Ligament Stem Cells via Toll-Like Receptors 4 (TLR4)/Nuclear Factor kappa B (NF-κB) Pathway

Yan Duan, Wei An [...]

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27 Jan 2019 : Laboratory Research

Adiponectin Relieves Human Adult Cardiac Myocytes Injury Induced by Intermittent Hypoxia

Xiaofeng Zhang, Lijun Rui [...]

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Med Sci Monit 2019; 25:786-793

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15 Apr 2019 : Animal Research

Avicularin Relieves Depressive-Like Behaviors Induced by Chronic Unpredictable Mild Stress in Mice

Zhongfei Shen, Yun Xu [...]

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Med Sci Monit 2019; 25:2777-2784

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01 Dec 2019 : Animal Research

Ulinastatin Reduces the Severity of Intestinal Damage in the Neonatal Rat Model of Necrotizing Enterocolitis

Shuxia Liang, Panjian Lai [...]

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05 Jan 2019 : Laboratory Research

β-Casomorphin-7 Ameliorates Sepsis-Induced Acute Kidney Injury by Targeting NF-κB Pathway

ZhiJie Zhang, Huatang Zhao [...]

DOI: 10.12659/MSM.912730

Med Sci Monit 2019; 25:121-127

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22 Oct 2019 : Animal Research

MD-1 Deficiency Accelerates Myocardial Inflammation and Apoptosis in Doxorubicin-Induced Cardiotoxicity by Activating the TLR4/MAPKs/Nuclear Factor kappa B (NF-κB) Signaling Pathway

Ying-Jun Zhang, He Huang [...]

DOI: 10.12659/MSM.919861

Med Sci Monit 2019; 25:7898-7907

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13 Mar 2019 : Laboratory Research

Effect of Montelukast on Bronchopulmonary Dysplasia (BPD) and Related Mechanisms

Xin Chen, Xiaoqian Zhang [...]

DOI: 10.12659/MSM.912774

Med Sci Monit 2019; 25:1886-1893

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22 Mar 2019 : Laboratory Research

Astragaloside IV Protects Against Oxidized Low-Density Lipoprotein (ox-LDL)-Induced Endothelial Cell Injury by Reducing Oxidative Stress and Inflammation

Zhongsheng Zhu, Jinyu Li [...]

DOI: 10.12659/MSM.912894

Med Sci Monit 2019; 25:2132-2140

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15 Feb 2019 : Animal Research

Simvastatin Improves Cardiac Hypertrophy in Diabetic Rats by Attenuation of Oxidative Stress and Inflammation Induced by Calpain-1-Mediated Activation of Nuclear Factor-κB (NF-κB)

QianQian Han, QianQian Liu [...]

DOI: 10.12659/MSM.913244

Med Sci Monit 2019; 25:1232-1241

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01 Mar 2019 : Animal Research

Renal-Protective Effects of the Peroxisome Proliferator-Activated Receptor-γ Agonist Pioglitazone in ob/ob Mice

Ying Li, Tian Xia [...]

DOI: 10.12659/MSM.913461

Med Sci Monit 2019; 25:1582-1589

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25 Apr 2019 : Clinical Research

Long-Term Intensive Lifestyle Intervention Promotes Improvement of Stage III Diabetic Nephropathy

Li Dong, Jie Li [...]

DOI: 10.12659/MSM.913512

Med Sci Monit 2019; 25:3061-3068

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21 Sep 2018 : Laboratory Research

Sinomenine Regulates Inflammatory Response and Oxidative Stress via Nuclear Factor kappa B (NF-κB) and NF-E2-Related Factor 2 (Nrf2) Signaling Pathways in Ankle Fractures in Children

Jie Shen, Rong Yao [...]

DOI: 10.12659/MSM.910740

Med Sci Monit 2018; 24: LBR6649-6655

1231 11 31

06 Sep 2018 : Laboratory Research

Rosiglitazone Reduces Apoptosis and Inflammation in Lipopolysaccharide-Induced Human Umbilical Vein Endothelial Cells

Xiao-xia Ji, Xiao-jing Ji [...]

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Med Sci Monit 2018; 24: LBR6200-6207

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05 Sep 2018 : Animal Research

Modulation of P2X Purinoceptor 3 (P2X3) in Pentylenetetrazole-Induced Kindling Epilepsy in Rats

Jie Xia, Hui Wang [...]

DOI: 10.12659/MSM.910352

Med Sci Monit 2018; 24: ANS6165-6177

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02 Aug 2018 : Animal Research

Baicalein Protects Rats with Diabetic Cardiomyopathy Against Oxidative Stress and Inflammation Injury via Phosphatidylinositol 3-Kinase (PI3K)/AKT Pathway

Lin Ma, Xiang Peng Li [...]

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Med Sci Monit 2018; 24: ANS5368-5375

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12 Jul 2018 : Laboratory Research

Genistein and Myd88 Activate Autophagy in High Glucose-Induced Renal Podocytes In Vitro

Yuanyuan Wang, Ying Li [...]

DOI: 10.12659/MSM.910868

Med Sci Monit 2018; 24: LBR4823-4831

1697 15 35

31 May 2018 : Animal Research

Protective Effects of Sinomenine Against Ankylosing Spondylitis and the Underlying Molecular Mechanisms

Bo Dong,

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Med Sci Monit 2018; 24: ANS3631-3636

1257 9 28

16 May 2018 : Laboratory Research

Ripasudil Attenuates Lipopolysaccharide (LPS)-Mediated Apoptosis and Inflammation in Pulmonary Microvascular Endothelial Cells via ROCK2/eNOS Signaling

Jianxin Yang, Feng Ruan [...]

DOI: 10.12659/MSM.910184

Med Sci Monit 2018; 24: LBR3212-3219

1644 29 49

14 May 2018 : Laboratory Research

Ginkgo Biloba L. Extract Reduces H2O2-Induced Bone Marrow Mesenchymal Stem Cells Cytotoxicity by Regulating Mitogen-Activated Protein Kinase (MAPK) Signaling Pathways and Oxidative Stress

Ao Wang, Qiwei Yang [...]

DOI: 10.12659/MSM.910718

Med Sci Monit 2018; 24: LBR3159-3167

1492 16 38

30 Apr 2018 : Hypothesis

Effect of Hexadecyl Azelaoyl Phosphatidylcholine on Cardiomyocyte Apoptosis in Myocardial Ischemia-Reperfusion Injury: A Hypothesis

Limin Feng, Wennan Liu [...]

DOI: 10.12659/MSM.907578

Med Sci Monit 2018; 24: HYP2661-2667

1672 7 32

25 Apr 2018 : Animal Research

Salvianolic Acid B Suppresses Inflammatory Mediator Levels by Downregulating NF-κB in a Rat Model of Rheumatoid Arthritis

Zeng-Bing Xia, Yong-Jian Yuan [...]

DOI: 10.12659/MSM.907084

Med Sci Monit 2018; 24: ANS2524-2532

1605 15 41

24 Mar 2018 : Laboratory Research

β-Arrestin 1/2 Aggravates Podocyte Apoptosis of Diabetic Nephropathy via Wnt/β-Catenin Pathway

Yao Wang, Han Li [...]

DOI: 10.12659/MSM.905642

Med Sci Monit 2018; 24: LBR1724-1732

1729 18 24

20 Mar 2018 : Animal Research

Specific Inhibitor of Smad3 (SIS3) Attenuates Fibrosis, Apoptosis, and Inflammation in Unilateral Ureteral Obstruction Kidneys by Inhibition of Transforming Growth Factor β (TGF-β)/Smad3 Signaling

Xingli Ji, Honglian Wang [...]

DOI: 10.12659/MSM.909236

Med Sci Monit 2018; 24: ANS1633-1641

2011 51 30

17 Mar 2018 : Animal Research

Sinomenine Attenuates Chronic Intermittent Hypoxia-Induced Lung Injury by Inhibiting Inflammation and Oxidative Stress

Xiaofeng Zhang, Lijun Rui [...]

DOI: 10.12659/MSM.906577

Med Sci Monit 2018; 24: ANS1574-1580

1485 8 36

20 Dec 2018 : Animal Research

Human Umbilical Cord Wharton’s Jelly Derived Mesenchymal Stromal Cells May Attenuate Sarcopenia in Aged Mice Induced by Hindlimb Suspension

Quan-Quan Wang, Xiao-Ma Jing [...]

DOI: 10.12659/MSM.913362

Med Sci Monit 2018; 24: ANS9272-9281

2143 47 36

22 Feb 2018 : Laboratory Research

Resveratrol Attenuates Cognitive Deficits of Traumatic Brain Injury by Activating p38 Signaling in the Brain

Zhenhua Shi, Wusi Qiu [...]

DOI: 10.12659/MSM.909042

Med Sci Monit 2018; 24: LBR1097-1103

1528 21 51

02 Oct 2018 : Animal Research

Diosmetin Attenuates Akt Signaling Pathway by Modulating Nuclear Factor Kappa-Light-Chain-Enhancer of Activated B Cells (NF-κB)/Inducible Nitric Oxide Synthase (iNOS) in Streptozotocin (STZ)-Induced Diabetic Nephropathy Mice

Yingsong Jiang, Jiguo Liu [...]

DOI: 10.12659/MSM.910764

Med Sci Monit 2018; 24: ANS7007-7014

1681 29 23

09 Jan 2018 : Laboratory Research

Gremlin Regulates Podocyte Apoptosis via Transforming Growth Factor-β (TGF-β) Pathway in Diabetic Nephropathy

Xiao-Bing Wang, Hong Zhu [...]

DOI: 10.12659/MSM.905758

Med Sci Monit 2018; 24: LBR183-189

1264 15 25

27 Sep 2018 : Laboratory Research

CD36 Promotes Podocyte Apoptosis by Activating the Pyrin Domain-Containing-3 (NLRP3) Inflammasome in Primary Nephrotic Syndrome

Xuejun Yang, You Wu [...]

DOI: 10.12659/MSM.909810

Med Sci Monit 2018; 24: LBR6832-6839

1781 29 20

08 Jan 2018 : Animal Research

Methylene Blue Exerts Anticonvulsant and Neuroprotective Effects on Self-Sustaining Status Epilepticus (SSSE) Induced by Prolonged Basolateral Amygdala Stimulation in Wistar Rats

Zhi-qiang Cui, Wen-ling Li [...]

DOI: 10.12659/MSM.907758

Med Sci Monit 2018; 24: ANS161-169

1211 6 36

Editorial

01 April 2024 : Editorial  

Editorial: Forty Years of Waiting for Prevention and Cure of HIV Infection – Ongoing Challenges and Hopes for Vaccine Development and Overcoming Antiretroviral Drug Resistance

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Med Sci Monit 2024; 30:e944600

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In Press

15 Apr 2024 : Laboratory Research  

The Role of Copper-Induced M2 Macrophage Polarization in Protecting Cartilage Matrix in Osteoarthritis

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07 Mar 2024 : Clinical Research  

Knowledge of and Attitudes Toward Clinical Trials: A Questionnaire-Based Study of 179 Male Third- and Fourt...

Med Sci Monit In Press; DOI: 10.12659/MSM.943468  

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08 Mar 2024 : Animal Research  

Modification of Experimental Model of Necrotizing Enterocolitis (NEC) in Rat Pups by Single Exposure to Hyp...

Med Sci Monit In Press; DOI: 10.12659/MSM.943443  

0:00

18 Apr 2024 : Clinical Research  

Comparative Analysis of Open and Closed Sphincterotomy for the Treatment of Chronic Anal Fissure: Safety an...

Med Sci Monit In Press; DOI: 10.12659/MSM.944127  

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Most Viewed Current Articles

17 Jan 2024 : Review article  

Vaccination Guidelines for Pregnant Women: Addressing COVID-19 and the Omicron Variant

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14 Dec 2022 : Clinical Research  

Prevalence and Variability of Allergen-Specific Immunoglobulin E in Patients with Elevated Tryptase Levels

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Med Sci Monit 2022; 28:e937990

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16 May 2023 : Clinical Research  

Electrophysiological Testing for an Auditory Processing Disorder and Reading Performance in 54 School Stude...

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Med Sci Monit 2023; 29:e940387

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01 Jan 2022 : Editorial  

Editorial: Current Status of Oral Antiviral Drug Treatments for SARS-CoV-2 Infection in Non-Hospitalized Pa...

DOI :10.12659/MSM.935952

Med Sci Monit 2022; 28:e935952

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Medical Science Monitor eISSN: 1643-3750
Medical Science Monitor eISSN: 1643-3750