30 June 2014 : Original article
Monocyte chemoattractant protein-1 gene (MCP-1-2518 A/G) polymorphism and serological markers of hepatitis B virus infection in hemodialysis patients
Alicja E. Grzegorzewska ABCDEFG , Dominik Pajzderski BCE , Anna Sowińska C , Paweł P. Jagodziński ACGDOI: 10.12659/MSM.891009
Med Sci Monit 2014; 20:1101-1116
Supplementary Table 4 Comparison of the distribution of MCP1 rs1024611 polymorphic variants in anti-HBs-negative hemodialysis (HD) patients despite vaccination or infection.
| Genotype | Anti-HBs negative HD patients despite vaccination (frequency) | Anti-HBs negative HD patients despite infection (frequency) | Odds ratio (95%CI) | Two-tailed P | Ptrend | Pgenotyping | Power (%) |
|---|---|---|---|---|---|---|---|
| All HD patients | |||||||
| n=153 | n=43 | ||||||
| AA | 65 (0.42) | 20 (0.47) | Referent | – | 0.845 | 0.786 | |
| AG | 73 (0.48) | 18 (0.42) | 0.801 (0.365–1.752) | 0.674 | 8.4 | ||
| GG | 15 (0.10) | 5 (0.11) | 1.083 (0.273–3.662) | 1.000 | 4.0 | ||
| AG+GG | 88 (0.57) | 23 (0.53) | 0.849 (0.408–1.782) | 0.764 | 5.9 | ||
| MAF | 103 (0.34) | 28 (0.33) | 0.952 (0.549–1.624) | 0.957 | 4.4 | ||
| AA | 44 (0.42) | 16 (0.50) | Referent | – | 0.680 | 0.511 | |
| AG | 52 (0.49) | 12 (0.38) | 0.635 (0.246–1.160) | 0.402 | 13.7 | ||
| GG | 10 (0.09) | 4 (0.13) | 1.100 (0.220–4.536) | 1.000 | 3.5 | ||
| AG+GG | 62 (0.58) | 16 (0.50) | 0.710 (0.297–1.699) | 0.517 | 11.8 | ||
| MAF | 72 (0.34) | 20 (0.31) | 0.884 (0.478–1.666) | 0.808 | 5.5 | ||
| AA | 21 (0.45) | 4 (0.36) | Referent | – | 0.757 | 0.839 | |
| AG | 21 (0.45) | 6 (0.55) | 1.500 (0.301–8.269) | 0.832 | 5.6 | ||
| GG | 5 (0.11) | 1 (0.09) | 1.050 (0.018–14.37) | 1.000 | 1.9 | ||
| AG+GG | 26 (0.55) | 7 (0.64) | 1.413 (0.307–7.465) | 0.879 | 6.3 | ||
| MAF | 31 (0.33) | 8 (0.36) | 1.161 (0.379–3.345) | 0.945 | 4.9 | ||
| anti-HBs – antibodies to surface antigen of hepatitis B virus; DM – diabetes mellitus; MAF – minor allele frequency. | |||||||