30 June 2014 : Original article
Monocyte chemoattractant protein-1 gene (MCP-1-2518 A/G) polymorphism and serological markers of hepatitis B virus infection in hemodialysis patients
Alicja E. Grzegorzewska ABCDEFG , Dominik Pajzderski BCE , Anna Sowińska C , Paweł P. Jagodziński ACGDOI: 10.12659/MSM.891009
Med Sci Monit 2014; 20:1101-1116
Supplementary Table 7 Comparison of the distribution of MCP1 rs1024611 polymorphic variants in all anti-HBc positive HD patients as well as in non-DM and DM patients to respective genotype frequencies in controls.
| Genotype | HD patients (frequency) | Controls (frequency) | Odds ratio (95%CI) | Two-tailed P | Ptrend | Pgenotyping | Power (%) |
|---|---|---|---|---|---|---|---|
| All HD patients | |||||||
| n=170 | n=437 | ||||||
| AA | 87 (0.51) | 225 (0.51) | Referent | – | 0.693 | 0.721 | |
| AG | 66 (0.39) | 177 (0.41) | 0.964 (0.650–1.428) | 0.927 | 4.8 | ||
| GG | 17 (0.10) | 35 (0.08) | 1.256 (0.625–2.443) | 0.578 | 10.1 | ||
| AG+GG | 83 (0.49) | 212 (0.49) | 1.013 (0.699–1.466) | 1.000 | 4.7 | ||
| MAF | 100 (0.29) | 247 (0.28) | 1.058 (0.793–1.405) | 0.740 | 6.5 | ||
| AA | 66 (0.54) | 225 (0.51) | Referent | – | 0.905 | 0.613 | |
| AG | 44 (0.36) | 177 (0.41) | 0.848 (0.537–1.329) | 0.519 | 10.2 | ||
| GG | 12 (0.10) | 35 (0.08) | 1.169 (0.522–2.466) | 0.790 | 6.6 | ||
| AG+GG | 56 (0.46) | 212 (0.49) | 0.901 (0.589–1.373) | 0.684 | 6.7 | ||
| MAF | 68 (0.28) | 247 (0.28) | 0.981 (0.703–1.358) | 0.973 | 4.6 | ||
| AA | 21 (0.44) | 225 (0.51) | Referent | – | 0.297 | 0.573 | |
| AG | 22 (0.46) | 177 (0.41) | 1.332 (0.674–2.634) | 0.463 | 12.0 | ||
| GG | 5 (0.10) | 35 (0.08) | 1.531 (0.423–4.538) | 0.579 | 11.7 | ||
| AG+GG | 27 (0.56) | 212 (0.49) | 1.365 (0.718–2.621) | 0.387 | 17.0 | ||
| MAF | 32 (0.33) | 247 (0.28) | 1.269 (0.782–2.025) | 0.355 | 17.1 | ||
| anti-HBc – antibodies to core antigen of hepatitis B virus; DM – diabetes mellitus, hemodialysis; HD – hemodialysis; MAF – minor allele frequency. | |||||||