30 June 2014 : Original article
Monocyte chemoattractant protein-1 gene (MCP-1-2518 A/G) polymorphism and serological markers of hepatitis B virus infection in hemodialysis patients
Alicja E. Grzegorzewska ABCDEFG , Dominik Pajzderski BCE , Anna Sowińska C , Paweł P. Jagodziński ACGDOI: 10.12659/MSM.891009
Med Sci Monit 2014; 20:1101-1116
Supplementary Table 1 The distribution of MCP1 rs1024611 genotypes in anti-HBc positive HD patients in respect to HWE.
| MCP1 rs1024611 genotype frequencies | All HD cases | HD cases without DM | HD cases with DM | |||
|---|---|---|---|---|---|---|
| Observed | Expected | Observed | expected | Observed | expected | |
| AA | 87 (0.51) | 85 (0.50) | 66 (0.54) | 63 (0.52) | 21 (0.44) | 21 (0.44) |
| AG | 66 (0.39) | 70 (0.41) | 44 (0.36) | 49 (0.40) | 22 (0.46) | 21 (0.44) |
| GG | 17 (0.10) | 15 (0.09) | 12 (0.10) | 10 (0.08) | 5 (0.10) | 6 (0.12) |
| P value for deviation from HWE | 0.397 | 0.256 | 0.829 | |||
| AA | 67 (0.53) | 65 (0.51) | 50 (0.56) | 48 (0.53) | 17 (0.46) | 17 (0.46) |
| AG | 48 (0.38) | 52 (0.41) | 32 (0.35) | 35 (0.39) | 16 (0.43) | 16 (0.43) |
| GG | 12 (0.09) | 10 (0.08) | 8 (0.09) | 7 (0.08) | 4 (0.11) | 4 (0.11) |
| P value for deviation from HWE | 0.433 | 0.388 | 0.935 | |||
| AA | 20 (0.46) | 19 (0.44) | 16 (0.50) | 15 (0.47) | 4 (0.35) | 5 (0.45) |
| AG | 18 (0.42) | 19 (0.44) | 12 (0.38) | 14 (0.44) | 6 (0.55) | 5 (0.45) |
| GG | 5 (0.12) | 5 (0.12) | 4 (0.12) | 3 (0.09) | 1 (0.10) | 1 (0.10) |
| P value for deviation from HWE | 0.759 | 0.472 | 0.554 | |||
| anti-HBc – antibodies to core antigen of hepatitis B virus; anti-HBs – antibodies to surface antigen of hepatitis B virus; DM – diabetes mellitus; HD – hemodialysis; HWE – Hardy-Weinberg equilibrium. | ||||||