30 June 2014 : Original article
Monocyte chemoattractant protein-1 gene (MCP-1-2518 A/G) polymorphism and serological markers of hepatitis B virus infection in hemodialysis patients
Alicja E. Grzegorzewska ABCDEFG , Dominik Pajzderski BCE , Anna Sowińska C , Paweł P. Jagodziński ACGDOI: 10.12659/MSM.891009
Med Sci Monit 2014; 20:1101-1116
Supplementary Table 3 Comparison of the distribution of MCP1 rs1024611 polymorphic variants in anti-HBs-positive HD due to vaccination or infection
| Genotype | Anti-HBs positive HD patients due to vaccination (frequency) | Anti-HBs positive HD patients due to infection (frequency) | Odds ratio (95%CI) | Two-tailed P | Ptrend | Pgenotyping | Power (%) |
|---|---|---|---|---|---|---|---|
| All HD patients | |||||||
| n=601 | n=127 | ||||||
| AA | 284 (0.47) | 67 (0.53) | Referent | – | 0.693 | 0.143 | |
| AG | 279 (0.46) | 48 (0.38) | 0.729 (0.475–1.115) | 0.153 | 30.1 | ||
| GG | 38 (0.07) | 12 (0.09) | 1.339 (0.603–2.790) | 0.520 | 12.0 | ||
| AG+GG | 317 (0.53) | 60 (0.47) | 0.802 (0.536–1.199) | 0.303 | 18.1 | ||
| MAF | 355 (0.29) | 72 (0.28) | 0.944 (0.689–1.284) | 0.768 | 6.0 | ||
| AA | 201 (0.47) | 50 (0.56) | Referent | – | 0.505 | 0.073 | |
| AG | 203 (0.48) | 32 (0.36) | 0.634 (0.377–1.055) | 0.082 | 41.6 | ||
| GG | 22 (0.05) | 8 (0.09) | 1.462 (0.530–3.659) | 0.518 | 13.1 | ||
| AG+GG | 225 (0.53) | 40 (0.44) | 0.715 (0.440–1.157) | 0.184 | 29.8 | ||
| MAF | 247 (0.29) | 48 (0.27) | 0.891 (0.606–1.293) | 0.596 | 8.6 | ||
| AA | 83 (0.47) | 17 (0.46) | Referent | – | 0.789 | 0.949 | |
| AG | 76 (0.43) | 16 (0.43) | 1.028 (0.451–2.334) | 1.000 | 3.5 | ||
| GG | 16 (0.09) | 4 (0.11) | 1.221 (0.264–4.460) | 0.961 | 5.2 | ||
| AG+GG | 92 (0.53) | 20 (0.54) | 1.061 (0.491–2.316) | 1.000 | 4.8 | ||
| MAF | 108 (0.31) | 24 (0.32) | 1.076 (0.600–1.889) | 0.890 | 5.1 | ||
| anti-HBs – antibodies to surface antigen of hepatitis B virus; DM – diabetes mellitus; MAF – minor allele frequency. | |||||||