30 October 2015 : Animal Research
Self-Assembled Cubic Liquid Crystalline Nanoparticles for Transdermal Delivery of Paeonol
Jian-Chun Li ABCDE , Na Zhu BC , Jin-Xiu Zhu CD , Wen-Jing Zhang DE , Hong-Min Zhang EF , Qing-Qing Wang FG , Xiao-Xiang Wu CE , Xiu Wang BFG , Jin Zhang BDE , Ji-Fu Hao ADGDOI: 10.12659/MSM.894484
Med Sci Monit 2015; 21:3298-3310
Supplementary Table 1. Storage stability of paeonol cubosome (n=3).
| Group | Drug amount (μg/ml) | Particle size (nm) | Zeta potential (mv) | Encapsulation efficiency (%) | |
|---|---|---|---|---|---|
| Before experiment | 21.60±0.52 | 82.09±2.03 | −31.2±2.61 | 92.35 | |
| After experiment | 24 h | 21.54±0.36 | 82.61±1.37 | −30.5±0.96 | 91.76 |
| A month at −20°C | 16.13±0.55 | 83.56±3.95 | −35.7±3.64 | 90.02 | |
| A month at 2–8°C | 20.85±0.38 | 80.12±2.28 | −33.5±1.56 | 92.07 | |
| A month at room temperature | 21.27±0.19 | 82.19±1.33 | −32.1±1.87 | 92.15 | |