17 July 2020 : Animal Research
The Effects of Timing of Postoperative Radiotherapy on Hypertrophic Scar in a Rabbit Model
Qiang Sun1ABG, Er-te Yu1BD, You Zhou1BD, Shuang Tong1C, Xu Sun1D, Ke-zhu Li1E, Meng-zhu Lv1F, Shu Guo1AG*DOI: 10.12659/MSM.921263
Med Sci Monit 2020; 26:e921263
Table 1 The study groups in the rabbit model and the effects of timing of radiotherapy on hypertrophic scar following surgery.
| No. of groups | Groups | Timing of the first radiotherapy | Cases of infection | |
|---|---|---|---|---|
| Non-infected | Infected | |||
| Group 1 | Non-resection group | – | – | – |
| Group 2 | Resection and non-radiotherapy group | – | 30 | 0 |
| Group 3 | Immediate postoperative radiotherapy group | Immediately after surgery | 29 | 1 |
| Group 4 | 12-hour postoperative radiotherapy group | 12 hours after surgery | 30 | 0 |
| Group 5 | 24-hour postoperative radiotherapy group | 24 hours after surgery | 30 | 0 |
| Group 6 | 48-hour postoperative radiotherapy group | 48 hours after surgery | 27 | 3 |
| Group 7 | 72-hour postoperative radiotherapy group | 72 hours after surgery | 29 | 1 |
| Group 8 | 120-hour postoperative radiotherapy group | 120 hours after surgery | 28 | 2 |