05 July 2020: Animal Study
Therapeutic Effect of Berberine on Insomnia Rats by ErbB Signaling Pathway
Qingquan Wang 1ABE , Xiaojuan Ren 1C , Xingping Zhang 1DG* , Guanying Wang 1D , Hongxia Xu 1C , Ning Deng 2F , Tao Liu 1D , Zhipeng Peng 1BDOI: 10.12659/MSM.921831
Med Sci Monit 2020; 26:e921831
Table 3 Metabolic signaling pathways involving genes expressed in rat hippocampus after drug treatment.
| Berberine treatment | Diazepam treatment |
|---|---|
| KEGG glycerolipid metabolism | KEGG inositol phosphateKEGG metabolism |
| KEGG inositol phosphate metabolism | KEGG glycerolipid metabolism |
| KEGG glycerophospholipid metabolism | KEGG beta alanine metabolism |
| KEGG ether lipid metabolism | KEGG glycerophospholipid metabolism |
| KEGG propanoate metabolism | KEGG sphingolipid metabolism |
| KEGG sphingolipid metabolism | KEGG purine metabolism |
| KEGG purine metabolism | KEGG cysteine and methionine metabolism |
| KEGG drug metabolism other enzymes | KEGG propanoate metabolism |
| KEGG porphyrin and chlorophyll metabolism | KEGG alanine aspartate and glutamate metabolism |
| KEGG starch and sucrose metabolism | KEGG starch and sucrose metabolism |
| KEGG galactose metabolism | KEGG nicotinate and nicotinamide metabolism |
| KEGG alpha linolenic acid metabolism | KEGG tryptophan metabolism |
| KEGG beta alanine metabolism | |
| KEGG glycine serine and threonine metabolism | |
| KEGG butanoate metabolism | |
| KEGG nicotinate and nicotinamide metabolism | |
| KEGG linoleic acid metabolism |