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22 September 2020: Meta-Analysis

Prevalence and Prevention of Reproducibility Deficiencies in Life Sciences Research: Large-Scale Meta-Analyses

Nadine M. Mansour 12ABCDEF , E. Andrew Balas 1ACDE* , Frances M. Yang 3CDE , Marlo M. Vernon 4BCEF

DOI: 10.12659/MSM.922016

Med Sci Monit 2020; 26:e922016

Table 1 Baseline characteristics of the included studies.

AuthorYearCountryDeficiency GroupSample typeSizeAuthorYearCountryDeficiency GroupSample typeSize
Armstrong []25 2010USAMycoplasma contaminationHuman & animal cell cultures38225Mariotti []26 2008ItalyMycoplasma contamination & misidentificationHuman & animal cell lines37
Avram []27 1985USADesign, statistics, & reportingAnesthesia articles243McGarrity []28 1986USAMycoplasma contaminationCell cultures2589
Azari []29 2007IranMisidentificationHuman cell lines100McGuigan []30 1995UKDesign, statistics, & reportingPsychiatry research articles164
Berglind []31 2008SwedenMisidentificationHuman cancer cell lines384McKinney []32 1989USADesign, statistics, & reportingMedical research articles56
Bölske []33 1988SwedenMycoplasma contaminationCell cultures1424Mirjalili []34 2005IranMixed contaminationHuman and animal cell lines138
Capes-Davis []14 2010AustraliaMisidentificationHuman cell lines360Neville []35 2006USADesign, statistics, & reportingDermatology research articles155
Capes-Davis []36 2013AustraliaMisidentificationHuman cell lines1157Nour-Eldein []37 2016EgyptDesign, statistics, & reportingMedical Research articles60
Cobo []38 2007SpainMixed contaminationStem cell cultures151Olarerin-George []39 2015USAMycoplasma contaminationHuman & animal cell cultures484
Didion []40 2014USACross-, mixed contamination, & misidentificationMouse cell lines99Oliver []41 1989AustraliaDesign, statistics, & reportingSurgery research articles240
Drexler []42 1999GermanyCross-contaminationHuman hematopoietic cell lines189Onwuegbuzie []43 2002USADesign, statistics, & reportingEducational Research36
Drexler []15 2002GermanyContamination, cross-contamination, & falseHuman leukemia lymphoma cell lines1404Patel []44 2014IndiaDesign, statistics, & reportingBasic Medical articles128
Drexler []45 2003GermanyMisidentificationHuman leukemia lymphoma cell lines550Pienkowska []46 1998CanadaViral contaminationHuman cell lines75
Drexler []47 2010GermanyMycoplasma contamination & misidentificationHuman leukemia lymphoma cell lines1331Pilčèk []48 2003CzechDesign, statistics, & reportingBiomedical articles171
Drexler []49 2017GermanyMycoplasma contamination & misidentificationHuman leukemia lymphoma cell lines330Roulland-Dussoix []50 1994FranceMycoplasma contaminationCell cultures372
Ercan []51 2012TurkeyDesign, statistics, & reportingMedical sciences articles181Schweppe []52 2008USAMisidentificationHuman thyroid cancer cell lines40
Ercan []53 2015TurkeyDesign, statistics, & reportingMedical sciences articles217Šimundić []54 2009CroatiaDesign, statistics, & reportingMedical research articles55
Ercan []55 2017TurkeyDesign, statistics, & reportingVeterinary sciences articles204Spierenburg []56 1988NetherlandsMycoplasma contaminationAnimal cell lines115
Felson []57 1984USADesign, statistics, & reportingRheumatology research articles74Störmer []58 2009GermanyMycoplasma contaminationHuman cell lines176
Hanif []59 2011PakistanDesign, statistics, & reportingMedical sciences articles80Strasak []60 2007AustriaDesign, statistics, & reportingMedical sciences articles15
Hassan []61 2015IndiaDesign, statistics, & reportingMedical research articles2012Strasak []62 2007AustriaDesign, statistics, & reportingMedical sciences articles53
Hopert []63 1993GermanyMycoplasma contaminationContinuous cell lines42Teyssou []64 1993FranceMycoplasma contaminationAnimal cell cultures82
Huang []65 2017ChinaMisidentification & cross-contaminationTumor cell lines278Timenetsky []66 2006BrazilMycoplasma contaminationHuman cell cultures301
Hué []67 2010UKViral contaminationHuman cell lines411Uchio-Yamada []68 2017JapanMisidentificationMouse cell lines80
Hukku []69 1984USAMixed contaminationCell cultures275Uphoff []70 2002GermanyMycoplasma contaminationLeukemia lymphoma cell lines451
Ishikawa []71 2006JapanMycoplasma contaminationCell cultures337Uphoff []72 2010GermanyViral contaminationAnimal cell lines465
Jin []73 2010ChinaDesign, statistics, & reportingMedical research articles2913Uphoff []74 2015GermanyViral contaminationHuman cell lines577
Jung []75 2003USAMycoplasma contaminationHuman & animal+ cell lines15Van Kuppeveld []76 1994NetherlandsMycoplasma contaminationHuman & animal cell cultures95
Kazemiha []77 2009IranMycoplasma contaminationMammalian cell lines200Welch II []78 2002USADesign, statistics, & reportingOB/GYN research articles195
Kazemiha []79 2014IranMycoplasma contaminationHuman and animal cell lines40Welch []80 1996USADesign, statistics, & reportingOB/GYN research articles145
Korch []81 2012USAMisidentificationEndometrial & ovarian cancer51Wu []82 2011ChinaDesign, statistics, & reportingMedical research articles2145
Kurichi []83 2006USADesign, statistics, & reportingSurgery research articles187Ye []84 2015ChinaCross-contaminationHuman cell lines380
Lucena []22 2011SpainDesign, statistics, & reportingDentistry research studies226Yim []85 2010KoreaDesign, statistics, & reportingMedical research articles139
MacArthur []86 1984USADesign, statistics, & reportingMedical sciences articles64Yoshino []87 2006JapanMisidentificationHuman cell lines400
MacLeod []88 1999GermanyCross-contaminationHuman tumor cell lines252Zhao []89 2011USACross-contaminationHuman cell lines122

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Medical Science Monitor eISSN: 1643-3750
Medical Science Monitor eISSN: 1643-3750