27 June 2020: Lab/In Vitro Research
Rab7 Is Associated with Poor Prognosis of Gastric Cancer and Promotes Proliferation, Invasion, and Migration of Gastric Cancer Cells
Huiyong Liu ACEF , Jie Xu DE , Qingzhi Yao B , Zhongyi Zhang B , Qiaonan Guo B , Jianqing Lin ABCE*DOI: 10.12659/MSM.922217
Med Sci Monit 2020; 26:e922217
Table 1 Clinicopathologic characteristics of 115 GC patients according to the Rab7 expression.
| Variant | Total | Rab7 p value | |
|---|---|---|---|
| Low (44) | High (71) | ||
| Age (years) | 0.876 | ||
| 69 | 26 | 43 | |
| ≥60 | 46 | 18 | 28 |
| Sex | 0.622 | ||
| Male | 84 | 31 | 53 |
| Female | 31 | 13 | 18 |
| Tumor size (cm) | 0.125 | ||
| 70 | 24 | 46 | |
| ≥5 | 45 | 20 | 25 |
| Depth of tumor invasion | 0.255 | ||
| T2 | 9 | 4 | 5 |
| T3 | 14 | 8 | 6 |
| T4 | 92 | 32 | 60 |
| Lymph node metastasis | 0.001* | ||
| N0 | 22 | 9 | 13 |
| N1 | 23 | 5 | 18 |
| N2 | 20 | 2 | 18 |
| N3 | 50 | 28 | 22 |
| Clinical stage | 0.757 | ||
| I/II | 28 | 10 | 18 |
| III/IV | 87 | 34 | 53 |
| Differentiation | 0.001* | ||
| High | 16 | 10 | 6 |
| Middle | 8 | 7 | 1 |
| Low/undifferentiation | 91 | 27 | 64 |
| * Significant difference. | |||