27 June 2020 : Laboratory Research
Rab7 Is Associated with Poor Prognosis of Gastric Cancer and Promotes Proliferation, Invasion, and Migration of Gastric Cancer Cells
Huiyong Liu1ACEF, Jie Xu1DE, Qingzhi Yao1B, Zhongyi Zhang1B, Qiaonan Guo1B, Jianqing Lin1ABCE*DOI: 10.12659/MSM.922217
Med Sci Monit 2020; 26:e922217
Table 1 Clinicopathologic characteristics of 115 GC patients according to the Rab7 expression.
| Variant | Total | Rab7 p value | |
|---|---|---|---|
| Low (44) | High (71) | ||
| Age (years) | 0.876 | ||
| <60 | 69 | 26 | 43 |
| ≥60 | 46 | 18 | 28 |
| Sex | 0.622 | ||
| Male | 84 | 31 | 53 |
| Female | 31 | 13 | 18 |
| Tumor size (cm) | 0.125 | ||
| <5 | 70 | 24 | 46 |
| ≥5 | 45 | 20 | 25 |
| Depth of tumor invasion | 0.255 | ||
| T2 | 9 | 4 | 5 |
| T3 | 14 | 8 | 6 |
| T4 | 92 | 32 | 60 |
| Lymph node metastasis | 0.001* | ||
| N0 | 22 | 9 | 13 |
| N1 | 23 | 5 | 18 |
| N2 | 20 | 2 | 18 |
| N3 | 50 | 28 | 22 |
| Clinical stage | 0.757 | ||
| I/II | 28 | 10 | 18 |
| III/IV | 87 | 34 | 53 |
| Differentiation | 0.001* | ||
| High | 16 | 10 | 6 |
| Middle | 8 | 7 | 1 |
| Low/undifferentiation | 91 | 27 | 64 |
| * Significant difference. | |||