Involvement of p53, p21, and Caspase-3 in Apoptosis of Coronary Artery Smooth Muscle Cells in a Kawasaki Vasculitis Mouse Model

21 August 2020: Animal Study

Minghong Deng ^1ACE , Chunwang Lin ^1AE* , Xianglin Zeng ^1C , Jianping Zhang ^1BD , Fang Wen ^1C , Ziguang Liu ^2B , Haiyan Wu ^3B , Xiaofeng Wu ^4B

DOI: 10.12659/MSM.922429

Med Sci Monit 2020; 26:e922429

Table 1 Comparison of IRS values for p53, p21, Bcl2, and caspase-3 between the KD and control groups.

Group	n	p53 IRS	p21 IRS	Bcl2 IRS	Caspase-3 IRS
KD	12	5.33±0.90	5.07±0.70	4.43±0.51	5.60±0.50
Control	12	4.05±1.05	3.21±0.97	6.37±0.76	3.83±0.38
		4.61	5.30	5.79	5.24
		0.001	0.001	0.001	0.001