21 June 2020>: Database Analysis
Development and Validation of Prognostic Nomograms for Patients with Duodenal Neuroendocrine Neoplasms
Shenghong Sun BDEF* , Wei Wang ACDFG** , Chiyi He ABG*DOI: 10.12659/MSM.922613
Med Sci Monit 2020; 26:e922613
Table 3 Univariate and multivariate analyses of CSS in patients with D-NENs.
Characteristics | Cancer-specific survival | ||||||
---|---|---|---|---|---|---|---|
Univariate analysis | Multivariate analysis | ||||||
HR | 95% CI | P | HR | 95% CI | P | ||
Age | Ref | Ref | |||||
≥65 | 2.851 | 1.459–5.571 | 3.613 | 1.697–7.690 | |||
Race | White | Ref | Ref | ||||
Black | 0.723 | 0.331–1.578 | 0.415 | 0.535 | 0.214–1.336 | 0.181 | |
Other | 0.328 | 0.045–2.408 | 0.273 | 0.347 | 0.043–2.772 | 0.318 | |
Gender | Female | Ref | Ref | ||||
Male | 0.812 | 0.431–1.529 | 0.519 | 0.903 | 0.431–1.892 | 0.786 | |
Marital status | Married | Ref | Ref | ||||
Unmarried | 1.852 | 0.973–3.523 | 0.060 | 1.794 | 0.848–3.793 | 0.126 | |
Unknown | 0.697 | 0.093–5.245 | 0.726 | 0.598 | 0.075–4.748 | 0.627 | |
Year of diagnosis | 1988–2009 | Ref | Ref | ||||
2010–2015 | 0.414 | 0.209–0.822 | 0.323 | 0.149–0.702 | |||
Tumor grade | 1 | Ref | Ref | ||||
2 | 1.166 | 0.440–3.089 | 0.758 | 1.161 | 0.417–3.237 | 0.775 | |
3/4 | 17.507 | 8.625–35.537 | 9.342 | 3.539–24.659 | |||
Tumor size | Ref | Ref | |||||
1–2 cm | 1.883 | 0.740–4.788 | 0.184 | 1.586 | 0.508–4.945 | 0.427 | |
>2 cm | 7.948 | 3.357–18.815 | 3.308 | 0.861–12.703 | 0.081 | ||
T stage | T1 | Ref | Ref | ||||
T2 | 1.428 | 0.574–3.553 | 0.444 | 0.705 | 0.227–2.188 | 0.545 | |
T3 | 5.400 | 2.169–13.446 | 2.149 | 0.559–8.260 | 0.266 | ||
T4 | 12.925 | 5.675–29.436 | 3.446 | 0.946–12.555 | 0.061 | ||
N stage | N0 | Ref | Ref | ||||
N1 | 2.946 | 1.543–5.625 | 0.600 | 0.216–1.665 | 0.327 | ||
M stage | M0 | Ref | Ref | ||||
M1 | 4.376 | 1.915–10.000 | 3.586 | 1.299–9.899 | |||
Surgery | Yes | Ref | Ref | ||||
No/Unknown | 2.735 | 1.328–5.636 | 3.094 | 1.277–7.497 | |||
D-NENs – primary duodenal neuroendocrine neoplasms; Race: Other – American Indian & AK Native & Asian & Pacific Islander; Marital status: Unmarried – Single & Separated & Divorced & Widowed & Unmarried or Domestic Partner. |