Logo Medical Science Monitor

Call: +1.631.470.9640
Mon - Fri 10:00 am - 02:00 pm EST

Contact Us

Logo Medical Science Monitor Logo Medical Science Monitor Logo Medical Science Monitor

22 June 2020: Clinical Research

Retrospective Analysis of Clinical Outcomes in Patients with Immunoglobulin A Nephropathy and Persistent Hematuria Following Renin-Angiotensin System Blockade

Jingjing Chen 12ACE , Shao Liu 1ADE , Hui Xu 23AF* , Wei Wang 3BC , Yanyun Xie 3B , Wenbin Tang 3B , Qiongjing Yuan 3B , Li Zheng 4D , Lizhen Lin 35F , Shuangshuang Fu 6F , Jinmei Shen 7C

DOI: 10.12659/MSM.922839

Med Sci Monit 2020; 26:e922839

Table 3 Multivariate Cox regression analysis for the effect of RASB on the primary outcome of IgAN patients only with persistent hematuria initially.

ModelsAll (n=110)PPatients without hypertension (n=99)P
HR (95% CI)HR (95% CI)
Model 1*
 With RASB0.34 (0.16–0.75)0.010.23 (0.09–0.59)0.002
 Without RASBReference
Model 2**
 With RASB0.28 (0.12–0.65)0.0030.21 (0.08–0.55)0.002
 Without RASBReference
Model 3***
 With RASB0.22 (0.09–0.53)0.0010.17 (0.06–0.46)0.001
 Without RASBReference
* Adjusted by gender and age;
** adjusted by gender, age, hypertension, hyperuricemia, initial eGFR, duration from initial diagnosis to start of therapy and initial hematuria;
*** Model 2+Oxford classification factors (M, E, S, T and C).
RASB – renin–angiotensin system blockers; HR – hazard ratio; CI – confidence interval.

Your Privacy

We use cookies to ensure the functionality of our website, to personalize content and advertising, to provide social media features, and to analyze our traffic. If you allow us to do so, we also inform our social media, advertising and analysis partners about your use of our website, You can decise for yourself which categories you you want to deny or allow. Please note that based on your settings not all functionalities of the site are available. View our privacy policy.

Medical Science Monitor eISSN: 1643-3750
Medical Science Monitor eISSN: 1643-3750