22 June 2020: Clinical Research
Retrospective Analysis of Clinical Outcomes in Patients with Immunoglobulin A Nephropathy and Persistent Hematuria Following Renin-Angiotensin System Blockade
Jingjing Chen 12ACE , Shao Liu 1ADE , Hui Xu 23AF* , Wei Wang 3BC , Yanyun Xie 3B , Wenbin Tang 3B , Qiongjing Yuan 3B , Li Zheng 4D , Lizhen Lin 35F , Shuangshuang Fu 6F , Jinmei Shen 7CDOI: 10.12659/MSM.922839
Med Sci Monit 2020; 26:e922839
Table 4 Secondary outcomes of propensity-matched patients (n=103).
| Outcomes | Treatment group | Untreated group | P |
|---|---|---|---|
| All (n=103) | |||
| Decreased percentage of hematuria (%) | 93 (74–96) | 72 (–6–91) | 0.01 |
| Rate of eGFR decline (ml/min per 1.73 m/y) | 0.78 (−1.95–4.36) | 0.05 (−4.73–5.58) | 0.48 |
| Final systolic pressure (mmHg) | 118 (110–125) | 115 (107–121) | 0.38 |
| Final diastolic pressure (mmHg) | 76 (74–85) | 69 (63–80) | 0.17 |
| Patients without hypertension (n=93) | |||
| Decreased percentage of hematuria (%) | 91 (73–96) | 71 (–22–91) | 0.01 |
| Rate of eGFR decline (ml/min per 1.73 m/y) | 0.69 (−1.66–4.41) | −0.05 (−4.77–5.47) | 0.37 |
| Final systolic pressure (mmHg) | 118 (110–124) | 115 (106–121) | 0.45 |
| Final diastolic pressure (mmHg) | 76 (71–80) | 70 (65–80) | 0.48 |
| eGFR – estimated glomerular filtration rate. | |||