Increased Expression of T-Box Transcription Factor Protein 21 (TBX21) in Skin Cutaneous Melanoma Predicts Better Prognosis: A Study Based on The Cancer Genome Atlas (TCGA) and Genotype-Tissue Expression (GTEx) Databases

20 June 2020 : Database Analysis

Xingying Zhang^1ADE, Xin Wen^1ABE, Ning Feng^1DE, Aoxing Chen^1DE, Senbang Yao^1DF, Xin Ding^1ADFG*, Longzhen Zhang^1ADG

DOI: 10.12659/MSM.923087

Med Sci Monit 2020; 26:e923087

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Table 1 Clinical features of SKCM patients in TCGA database.

Clinical characteristics			Total (445)	Percent (%)
Age at diagnosis (years)	<58		217	48.76
Age at diagnosis (years)	≥58		228	51.24
Gender	Female		168	37.75
Gender	Male		277	62.25
Fustat	Live		207	47.09
Fustat	Death		238	52.91
Clinical stage	0		6	1.49
	I		77	19.15
	II		130	32.34
	III		169	42.04
	IV		20	4.98
T stage	Tis		7	1.74
	T0		23	5.72
	T1		66	16.42
	T2		76	18.91
	T3		88	21.89
	T4		142	35.32
Distant metastasis	Negative		400	95.01
Distant metastasis	Positive		21	4.99
Lymph nodes	Negative		221	55.67
	Positive	1	73	18.39
		2–3	49	12.34
		≥4	54	13.60
SKCM – skin cutaneous melanoma; TCGA – The Cancer Genome Atlas. The median age at diagnosis was 58 years old.

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