20 June 2020 : Database Analysis
Increased Expression of T-Box Transcription Factor Protein 21 (TBX21) in Skin Cutaneous Melanoma Predicts Better Prognosis: A Study Based on The Cancer Genome Atlas (TCGA) and Genotype-Tissue Expression (GTEx) Databases
Xingying Zhang1ADE, Xin Wen1ABE, Ning Feng1DE, Aoxing Chen1DE, Senbang Yao1DF, Xin Ding1ADFG*, Longzhen Zhang1ADGDOI: 10.12659/MSM.923087
Med Sci Monit 2020; 26:e923087
Table 2 Logistic regression analysis of the relationship between TBX21 expression and clinical factors.
| Clinical factors | Total (N) | OR (95% CI) | P-value | |
|---|---|---|---|---|
| Age (years) | ≥58 <58 | 445 | 0.9221 (0.6349–1.3386) | 0.6697 |
| Gender | Male Female | 445 | 0.7841 (0.5358–1.1456) | 0.2093 |
| Stage | II I | 216 | 0.4567 (0.2570–0.8031) | |
| III I | 246 | 0.8784 (0.5062–1.5138) | 0.6419 | |
| IV I | 99 | 0.9455 (0.3694–2.4707) | 0.9071 | |
| T stage | T2 T1 | 119 | 0.4643 (0.2053–1.0122) | 0.0581 |
| T3 T1 | 131 | 0.5306 (0.2383–1.1380) | 0.1101 | |
| T4 T1 | 193 | 0.3469 (0.1624–0.7089) | ||
| Lymph nodes | N1 N0 | 308 | 1.0320 (0.6104–1.7424) | 0.9062 |
| N2 N0 | 283 | 1.3369 (0.7214–2.5003) | 0.3577 | |
| N3 N0 | 288 | 1.3616 (0.7526–2.4855) | 0.3092 | |
| Distant metastasis | M1 M0 | 440 | 1.1932 (0.5218–2.7760) | 0.6749 |
| TBX21 – T-box transcription factor protein 21; OR – odds ratio; CI – confidence interval. | ||||