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20 June 2020 : Database Analysis  

Increased Expression of T-Box Transcription Factor Protein 21 (TBX21) in Skin Cutaneous Melanoma Predicts Better Prognosis: A Study Based on The Cancer Genome Atlas (TCGA) and Genotype-Tissue Expression (GTEx) Databases

Xingying Zhang1ADE, Xin Wen1ABE, Ning Feng1DE, Aoxing Chen1DE, Senbang Yao1DF, Xin Ding1ADFG*, Longzhen Zhang1ADG

DOI: 10.12659/MSM.923087

Med Sci Monit 2020; 26:e923087

Table 4 Gene set enrichment analysis.

NameNESNOM P-valFDR q-val
KEGG_Chemokine_Signaling_Pathway2.7256<0.001<0.001
KEGG_Cytokine_Cytokine_Receptor_Interaction2.6925<0.001<0.001
KEGG_Natural_Killer_Cell_Mediated_Cytotoxicity2.6638<0.001<0.001
KEGG_T_Cell_Receptor_Signaling_Pathway2.5619<0.001<0.001
KEGG_JAK_STAT_Signaling_Pathway2.5563<0.001<0.001
KEGG_TOLL_Like_Receptor_Signaling_Pathway2.5174<0.001<0.001
KEGG_Apoptosis2.4450<0.001<0.001
KEGG_B_Cell_Receptor_Signaling_Pathway2.4338<0.001<0.001
KEGG_MAPK_Signaling_Pathway1.8407<0.001<0.05
NES – normalized enrichment score; NOM -val – nominal -value; FDR q-val – false discovery rate q-value; KEGG – Kyoto Encyclopedia of Genes and Genomes. Gene sets with NOM -val

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Medical Science Monitor eISSN: 1643-3750
Medical Science Monitor eISSN: 1643-3750