25 June 2020 : Clinical Research
Serum Amyloid A: A Potential Biomarker Assessing Disease Activity in Systemic Lupus Erythematosus
Cai-Mei Wang1EFG, Jin-Huan Deng1EFG, Guo-Fei Mao1B, Yong-Ling He1B, Xiang Shi1AC*DOI: 10.12659/MSM.923290
Med Sci Monit 2020; 26:e923290
Table 2 Demographic and laboratory parameters in patients with systemic lupus erythematosus (SLE) with active disease and inactive disease.
| Patients with active SLE (n=52) | Patients with inactive SLE (n=83) | P-value | |
|---|---|---|---|
| Gender (Male/Female) | 6/46 | 8/75 | 0.725 |
| Age (years) | 38.1±13.9 | 38.2±13.0 | 0.978 |
| WBC (10/L) | 6.62 (4.33–10.22) | 5.31 (3.82–9.00) | 0.132 |
| RBC (10/L) | 4.01±0.65 | 4.16±0.68 | 0.210 |
| Platelet count (10/L) | 218.00 (153.50–302.50) | 225.00 (166.00–274.00) | 0.917 |
| Hemoglobin (g/L) | 111.0 (97.8–119.8) | 119.0 (109.0–128.0) | 0.019 |
| RDW (%) | 14.25 (13.20–17.08) | 13.20 (12.60–14.80) | 0.001 |
| Hs-CRP (mg/L) | 9.31 (6.14–24.04) | 0.74 (0.27–1.82) | <0.001 |
| ESR (mm/h) | 49.0 (29.3–74.3) | 12.0 (8.0–17.0) | <0.001 |
| SAA (mg/L) | 16.65 (9.35–39.68) | 2.3 0 (1.30–4.80) | <0.001 |
| WBC – white blood cell count; RBC – red blood cell; RDW – red blood cell distribution width; Hs-CRP – hypersensitive C-reactive protein; ESR – erythrocyte sedimentation rate; SAA – serum amyloid A. | |||