The Expression of Dynamin 1, 2, and 3 in Human Hepatocellular Carcinoma and Patient Prognosis

23 June 2020 : Clinical Research

Mei Tian^1BE, Xiuchun Yang^1CD, Yanfang Li^1BF, Sen Guo^2ABCDEFG*

DOI: 10.12659/MSM.923359

Med Sci Monit 2020; 26:e923359

Table 2 Correlation between Dynamin isoforms and the other characters.

Characters	Dynamin 1		P*	Dynamin 2		P*	Dynamin 3		P*
Characters	Low	High	P*	Low	High	P*	Low	High	P*
Sex
Female	14	5	0.221	13	6	0.798	17	2	0.662
Male	99	74		122	51		159	14
Age
	85	63	0.491	105	43	0.711	137	11	0.371
≥60	28	16		30	14		39	5
Tumor size (cm)
≤5	62	36	0.241	69	29	0.976	91	7	0.608
>5	51	43		66	28		85	9
Tumor number
Single	101	70	1.000	120	51	1.000	160	11	0.019
Multiple	12	9		15	6		16	5
Histopathological grade
I+II	73	50	0.876	87	36	0.871	111	12	0.423
III	40	29		48	21		65	4
Vascular invasion
Negative	81	46	0.053	89	38	1.000	115	12	0.584
Positive	32	33		46	19		61	4
HBsAg
Negative	27	23	0.504	36	14	0.858	43	7	0.133
Positive	86	56		99	43		133	9
HCV
Negative	108	71	0.149	127	52	0.473	164	15	1.000^#
Positive	5	8		8	5		12	1
AFP
	75	34	0.001	77	32	0.909	100	9	0.965
≥500 ng/ml	38	45		58	25		76	7
T stage
I+II	91	48	0.003	99	40	0.724	128	11	0.733
III+IV	22	31		36	17		48	5
Lymph invasion
Negative	113	77	0.168^#	135	55	0.087^#	174	16	0.554^#
Positive	0	2		0	2		2	0
TNM stage
I+II	92	48	0.002	100	40	0.579	129	11	0.695
III+IV	21	31		35	17		47	5
^* Analyzed with Chi-square test, ^# analyzed with the Fisher test. HBsAg – hepatitis B surface antigen; HCV – hepatitis C virus; AFP – alpha fetoprotein.