23 June 2020>: Clinical Research
The Expression of Dynamin 1, 2, and 3 in Human Hepatocellular Carcinoma and Patient Prognosis
Mei Tian 1BE* , Xiuchun Yang 1CD* , Yanfang Li 1BF , Sen Guo 2ABCDEFG*DOI: 10.12659/MSM.923359
Med Sci Monit 2020; 26:e923359
Table 3 Univariate analysis was performed to screen prognostic characters.
Characters | 5-year OS(%) | P* |
---|---|---|
Sex | ||
Female | 73.7 | 0.069 |
Male | 45.6 | |
Age | ||
45.8 | 0.215 | |
≥60 | 56.3 | |
Tumor size (cm) | ||
≤5 | 57.6 | |
>5 | 39.2 | |
Tumor number | ||
Single | 48.6 | 0.438 |
Multiple | 42.9 | |
Histopathological grade | ||
I+II | 50.7 | 0.249 |
III | 46.1 | |
Vascular invasion | ||
Negative | 55.8 | 0.001 |
Positive | 33.4 | |
HBsAg | ||
Negative | 50.6 | 0.949 |
Positive | 48.4 | |
HCV | ||
Negative | 48.5 | 0.521 |
Positive | 46.2 | |
AFP | ||
48.9 | 0.097 | |
≥500 ng/ml | 49.6 | |
T stage | ||
I+II | 59.7 | |
III+IV | 18.7 | |
Lymph invasion | ||
Negative | 48.9 | 0.108 |
Positive | 0.0 | |
TNM stage | ||
I+II | 59.2 | |
III+IV | 19.0 | |
Dynamin 1 | ||
Low | 58.4 | |
High | 34.0 | |
Dynamin 2 | ||
Low | 46.5 | 0.585 |
High | 52.6 | |
Dynamin 3 | ||
Low | 48.5 | 0.594 |
High | 43.8 | |
* Analyzed with log-rank test. HBsAg – hepatitis B surface antigen; HCV – hepatitis C virus; AFP – alpha fetoprotein. |