23 June 2020 : Clinical Research
The Expression of Dynamin 1, 2, and 3 in Human Hepatocellular Carcinoma and Patient Prognosis
Mei Tian1BE, Xiuchun Yang1CD, Yanfang Li1BF, Sen Guo2ABCDEFG*DOI: 10.12659/MSM.923359
Med Sci Monit 2020; 26:e923359
Table 3 Univariate analysis was performed to screen prognostic characters.
| Characters | 5-year OS(%) | P* |
|---|---|---|
| Sex | ||
| Female | 73.7 | 0.069 |
| Male | 45.6 | |
| Age | ||
| <60 | 45.8 | 0.215 |
| ≥60 | 56.3 | |
| Tumor size (cm) | ||
| ≤5 | 57.6 | <0.001 |
| >5 | 39.2 | |
| Tumor number | ||
| Single | 48.6 | 0.438 |
| Multiple | 42.9 | |
| Histopathological grade | ||
| I+II | 50.7 | 0.249 |
| III | 46.1 | |
| Vascular invasion | ||
| Negative | 55.8 | 0.001 |
| Positive | 33.4 | |
| HBsAg | ||
| Negative | 50.6 | 0.949 |
| Positive | 48.4 | |
| HCV | ||
| Negative | 48.5 | 0.521 |
| Positive | 46.2 | |
| AFP | ||
| <500 ng/ml | 48.9 | 0.097 |
| ≥500 ng/ml | 49.6 | |
| T stage | ||
| I+II | 59.7 | <0.001 |
| III+IV | 18.7 | |
| Lymph invasion | ||
| Negative | 48.9 | 0.108 |
| Positive | 0.0 | |
| TNM stage | ||
| I+II | 59.2 | <0.001 |
| III+IV | 19.0 | |
| Dynamin 1 | ||
| Low | 58.4 | <0.001 |
| High | 34.0 | |
| Dynamin 2 | ||
| Low | 46.5 | 0.585 |
| High | 52.6 | |
| Dynamin 3 | ||
| Low | 48.5 | 0.594 |
| High | 43.8 | |
| * Analyzed with log-rank test. HBsAg – hepatitis B surface antigen; HCV – hepatitis C virus; AFP – alpha fetoprotein. | ||