Effect of Red Blood Cell Storage Duration on Outcomes of Isolated Traumatic Brain Injury

Kun Xiao; Fei Zhao; Qiang Liu; Jinliang Jiang; Zhiyong Chen; Wei Gong; Zengwang Zheng; Aiping Le

doi:10.12659/MSM.923448

07 November 2020 : Clinical Research

Effect of Red Blood Cell Storage Duration on Outcomes of Isolated Traumatic Brain Injury

Kun Xiao^1AE, Fei Zhao^2AE, Qiang Liu^3B, Jinliang Jiang^4B, Zhiyong Chen^5C, Wei Gong^6D, Zengwang Zheng^7F, Aiping Le^1A*

DOI: 10.12659/MSM.923448

Med Sci Monit 2020; 26:e923448

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Table 3 Univariate regression analysis of 90-day mortality in patients with iTBI.

Variables	Univariate				Multivariate
	P	OR	95% CI		P	OR	95% CI
	P	OR	Lower	Upper	P	OR	Lower	Upper
Age	0.001	1.020	1.008	1.033	0.010	1.026	1.006	1.045
Gender (Male)	0.085	0.755	0.549	1.040	0.002	0.513	0.335	0.785
Weight	0.020	0.983	0.969	0.997	0.155	0.985	0.965	1.006
Fresh blood	0.262	1.192	0.877	1.620	0.231	1.252	0.867	1.808
Diabetes history	0.377	0.769	0.430	1.378	0.192	0.591	0.268	1.302
Hypertension history	<0.001	2.031	1.377	2.997	0.193	1.543	0.803	2.965
GCS score on admission	0.512	0.981	0.927	1.039	0.751	1.011	0.944	1.083
Head and neck AIS	0.801	1.025	0.846	1.242	0.739	1.039	0.831	1.298
ISS score	0.163	0.987	0.969	1.005	0.858	1.002	0.980	1.025
LOS in hospital	<0.001	1.197	1.163	1.233	<0.001	1.178	1.142	1.215
LOS in ICU	0.161	0.766	0.527	1.112	0.984	0.990	0.387	2.536
Mechanical ventilation	0.125	1.029	0.992	1.068	0.555	1.028	0.937	1.129
Brain injury
Subdural hematoma	Ref				Ref
Epidural hematoma	0.652	0.925	0.657	1.300	0.604	1.181	0.630	2.212
Subarachnoid hemorrhage	<0.001	0.286	0.156	0.524	0.005	0.332	0.153	0.722
Intracerebral hemorrhage	0.996	0.000	0.000	–	0.996	0.000	0.000	–
Intraventricular hemorrhage	0.039	2.053	1.037	4.063	0.017	3.027	1.219	7.515
Brain contusion	0.998	0.000	0.000	–	0.998	0.000	0.000	–
Diffuse axonal injury	0.331	0.360	0.046	2.821	0.325	0.258	0.017	3.838
Causes of injury
Non-accidental injury	Ref				Ref
Fall over injury	0.485	1.137	0.793	1.632	0.500	0.806	0.432	1.506
Traffic injury	0.035	0.563	0.330	0.959	0.253	1.500	0.748	3.006
High falling injury	0.255	0.774	0.498	1.203	0.036	0.528	0.291	0.958
iTBI – isolated traumatic brain injury; OR – odds ratio; CI – confidence interval; RBCs – red blood cells; GCS – Glasgow coma scale; AIS – abbreviated injury scale; ISS – injury severity score; LOS – the length of stay; ICU – Intensive Care Unit.

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Effect of Red Blood Cell Storage Duration on Outcomes of Isolated Traumatic Brain Injury

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