Efficacy of Primary Tumor Resection in Metastatic Colorectal Cancer

29 August 2020: Database Analysis

Yong Huang ^1BCEF* , Kuanxue Ge ^2BCD* , Guangshun Fu ^1F , Junfeng Chu ^3AB* , Wei Wei ^1AE*

DOI: 10.12659/MSM.923501

Med Sci Monit 2020; 26:e923501

Table 3 The results of multivariate Cox regression analyses of OS in the whole cohort.

Variable	Reference	Characteristic	Cancer-specific survival
Variable	Reference	Characteristic	HR (95% CI)	SE	P value
Age at diagnosis		≥65	1.397 (1.370–1.425)	0.010
Tumor location	Colon	Rectum	0.811 (0.793–0.829)	0.011
Surgery of the primary tumor	No	Yes	0.430 (0.417–0.443)	0.015
T stage	T1	T2	0.733 (0.681–0.790)	0.038
		T3	0.889 (0.854–0.925)	0.020
		T4	1.122 (1.079–1.168)	0.020
		Unknown	1.078 (1.039–1.119)	0.019
N stage	N0	N1	1.188 (1.158–1.220)	0.013
		N2	1.594 (1.548–1.641)	0.015
		Unknown	1.142 (1.107–1.178)	0.016
Race	White	Black	1.108 (1.079–1.138)	0.013
		Other	0.914 (0.883–0.946)	0.018
Gender	Male	Female	0.985 (0.967–1.004)	0.010	0.124
Year of diagnosis	2004	2005	1.024 (0.982–1.067)	0.021	0.262
		2006	0.989 (0.949–1.030)	0.021	0.595
		2007	1.000 (0.959–1.042)	0.021	0.995
		2008	0.987 (0.947–1.029)	0.021	0.535
		2009	0.924 (0.887–0.963)	0.021
		2010	0.932 (0.894–0.971)	0.021	0.001
		2011	0.977 (0.938–1.019)	0.021	0.282
		2012	0.911 (0.873–0.950)	0.021
		2013	0.904 (0.866–0.943)	0.022
Chemotherapy	No	Yes	0.459 (0.450–0.468)	0.010