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28 September 2020: Clinical Research

Catechol-O-Methyltransferase Gene Polymorphisms and the Risk of Chemotherapy-Induced Prospective Memory Impairment in Breast Cancer Patients with Varying Tumor Hormonal Receptor Expression

Wen Li 1ABCE , Jingjing Zhao 2B , Ke Ding 2B , Herta H. Chao 3E , Chiang-Shan R. Li 4BC , Huaidong Cheng 2AG* , Li Shen 5AG*

DOI: 10.12659/MSM.923567

Med Sci Monit 2020; 26:e923567

Table 2 Neuropsychological performance before and after chemotherapy.

TaskMean±SD
Before chemotherapy (n=232)After chemotherapy (n=232)
MMSE27.27±1.5726.65±1.64*
DST6.19±0.735.95±0.97**
VFT11.48±1.529.96±2.13**
EBPM2.72±1.012.00±1.19**
TBPM4.98 ± 0.974.75 ±0.91*
*
**
MMSE – Mini-Mental State Examination; DST – digit span test; VFT – verbal fluency test; EBPM – event-based prospective memory task; TBPM – time-based prospective memory task.

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Medical Science Monitor eISSN: 1643-3750
Medical Science Monitor eISSN: 1643-3750