Catechol-O-Methyltransferase Gene Polymorphisms and the Risk of Chemotherapy-Induced Prospective Memory Impairment in Breast Cancer Patients with Varying Tumor Hormonal Receptor Expression

28 September 2020 : Clinical Research

Wen Li^1ABCE, Jingjing Zhao^2B, Ke Ding^2B, Herta H. Chao^3E, Chiang-Shan R. Li^4BC, Huaidong Cheng^2AG*, Li Shen^5AG

DOI: 10.12659/MSM.923567

Med Sci Monit 2020; 26:e923567

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Table 3 Neuropsychological performance in patients with ER−/PR− and ER+/PR+.

Task	Mean±SD
Task	ER−/PR− (n=113)	ER+/PR+ (n=119)
MMSE	26.57±1.69	26.93±1.58^#
DST	5.49±1.05	5.99±0.83^**
VFT	8.89±1.84	10.97±1.90^**
EBPM	1.37±1.14	2.59±0.92^**
TBPM	4.73± 0.89	4.77 ±0.93^#
^# >0.05, ^** MMSE – Mini-Mental State Examination; DST – digit span test; VFT – verbal fluency test; EBPM – event-based prospective memory task; TBPM – time-based prospective memory task.

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