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28 September 2020: Clinical Research

Catechol-O-Methyltransferase Gene Polymorphisms and the Risk of Chemotherapy-Induced Prospective Memory Impairment in Breast Cancer Patients with Varying Tumor Hormonal Receptor Expression

Wen Li 1ABCE , Jingjing Zhao 2B , Ke Ding 2B , Herta H. Chao 3E , Chiang-Shan R. Li 4BC , Huaidong Cheng 2AG* , Li Shen 5AG*

DOI: 10.12659/MSM.923567

Med Sci Monit 2020; 26:e923567

Table 6 Correlation analysis between COMT (rs737865) and CICI.

ModelGenotypeB (95% CI)P-value
MMSEDominantA/A1.078 (0.92~1.264)0.351
RecessiveA/A+G/A0.971 (0.746~1.256)0.830
HOMA/A1.007 (0.767~1.319)0.958
HETG/A1.090 (0.920~1.292)0.318
DSTDominantA/A0.956 (0.73~1.25)0.746
RecessiveA/A+G/A0.841 (0.532~1.329)0.458
HOM0.843 (0.525~−1.353)0.478
HETG/A1.004 (0.754~−1.336)0.979
VFTDominantA/A0.949 (0.84~1.072)0.400
RecessiveA/A+G/A1.209 (0.977~1.496)0.081
HOMA/A1.168 (0.93~1.466)0.181
HETG/A0.910 (0.799~1.036)0.153
EBPMDominantA/A1.117 (0.898~1.388)0.321
RecessiveA/A+G/A1.499 (1.017~2.211)0.041
HOMA/A1.536 (1.02~2.313)0.040
HETG/A1.039 (0.826~1.306)0.745
TBPMDominantA/A0.941 (0.707~1.253)0.941
RecessiveA/A+G/A1.021 (0.627~1.663)0.934
HOMA/A1.002 (0.589~1.705)0.994
HETG/A0.959 (0.710~1.295)0.783
HOM – homozygote; HET – heterozygote; beta – regression coefficient; 95% CI – 95% confidence interval

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Medical Science Monitor eISSN: 1643-3750
Medical Science Monitor eISSN: 1643-3750