Kupffer Cells Regulate Natural Killer Cells Via the NK group 2, Member D (NKG2D)/Retinoic Acid Early Inducible-1 (RAE-1) Interaction and Cytokines in a Primary Biliary Cholangitis Mouse Model

Hai-Yan Fu; Wei-Min Bao; Cai-Xia Yang; Wei-Ju Lai; Jia-Min Xu; Hai-Yan Yu; Yi-Na Yang; Xu Tan; Ajay Kumar Gupta; Ying-Mei Tang

doi:10.12659/MSM.923726

29 June 2020 : Animal Research

Kupffer Cells Regulate Natural Killer Cells Via the NK group 2, Member D (NKG2D)/Retinoic Acid Early Inducible-1 (RAE-1) Interaction and Cytokines in a Primary Biliary Cholangitis Mouse Model

Hai-Yan Fu^1EF, Wei-Min Bao^2C, Cai-Xia Yang^1D, Wei-Ju Lai^1D, Jia-Min Xu^1B, Hai-Yan Yu^1B, Yi-Na Yang^1B, Xu Tan^1B, Ajay Kumar Gupta^1F, Ying-Mei Tang^1AG*

DOI: 10.12659/MSM.923726

Med Sci Monit 2020; 26:e923726

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Supplementary Table 1 Expression of NKG2D and RAE-1 in NK cells and Kupffer cells co-cultured in vitro.

	PBC	CON	t
NKG2D	2.83±0.25	0.63±0.08	26.5041
RAE-1	39.92±3.16	19.62±2.08	16.9686
NKG2D – natural killer group 2, member D; RAE-1 – retinoic acid early inducible-1; NK – natural killer; PBC – primary biliary cholangitis; CON – control.

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Kupffer Cells Regulate Natural Killer Cells Via the NK group 2, Member D (NKG2D)/Retinoic Acid Early Inducible-1 (RAE-1) Interaction and Cytokines in a Primary Biliary Cholangitis Mouse Model

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