23 July 2020 : Clinical Research
Clinicopathological Analysis and Prognostic Assessment of Transcobalamin I (TCN1) in Patients with Colorectal Tumors
Xinqiang Zhu12ABCDEG*, Kui Yi3BE, Daorong Hou4ADF, Hailong Huang2BC, Xuetong Jiang2ABE, Xiaohong Shi2BCE, Chungen Xing1AEFDOI: 10.12659/MSM.923828
Med Sci Monit 2020; 26:e923828
Table 1 Clinicopathologic data.
| Parameters | Number of cases | Percentage |
|---|---|---|
| Age | ||
| <65 years | 78 | 63.4 |
| ≥65 years | 45 | 36.6 |
| Mean±SD | 53.61±2.128 | |
| Median | 61 | |
| Age range | 39–81 | |
| Sex | ||
| Female | 57 | 46.3 |
| Male | 66 | 53.7 |
| CEA level | ||
| Increased | 45 | 36.6 |
| Normal | 78 | 63.7 |
| CA125 level | ||
| Increased | 27 | 22.0 |
| Normal | 96 | 78.0 |
| CA19-9 level | ||
| Increased | 24 | 19.5 |
| Normal | 99 | 80.5 |
| Tumor location | ||
| Colon | 30 | 24.4 |
| Distal colon | 27 | 22.0 |
| Rectum | 66 | 53.6 |
| Histological differentiation | ||
| G1 | 30 | 24.4 |
| G2 | 48 | 39.0 |
| G3 | 45 | 36.6 |
| Depth of invasion | ||
| T1/T2 | 21 | 17.1 |
| T3/T4 | 102 | 82.9 |
| Tumor size | ||
| <5 cm | 66 | 53.7 |
| ≥5 cm | 57 | 46.3 |
| Metastases to regional lymph nodes | ||
| No | 66 | 53.7 |
| Yes | 57 | 46.3 |
| Nerve invasion | ||
| No | 75 | 61.0 |
| Yes | 48 | 39.0 |
| Adjuvant chemotherapy | ||
| No | 5 | 4.1 |
| Yes | 118 | 95.9 |
| CEA – carcinoembryonic antigen; CA125 – cancer antigen 125; CA19-19 – cancer antigen 19-9. | ||