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23 July 2020 : Clinical Research  

Clinicopathological Analysis and Prognostic Assessment of Transcobalamin I (TCN1) in Patients with Colorectal Tumors

Xinqiang Zhu12ABCDEG*, Kui Yi3BE, Daorong Hou4ADF, Hailong Huang2BC, Xuetong Jiang2ABE, Xiaohong Shi2BCE, Chungen Xing1AEF

DOI: 10.12659/MSM.923828

Med Sci Monit 2020; 26:e923828

Table 5 Multivariate analysis of various prognostic parameters in CRC patients with Cox regression analysis.

Prognostic parametersHR95% CIP value
Age (≥65 <65)4.3291.194–15.6950.026
Sex (Male Female)
CEA1.492.532–4.1970.447
CA1253.7321.371–10.1540.010
CA19-96.0452.017–18.1190.001
Tumor grading16.1326.673–43.9900.065
Depth of invasion0.7630.413–1.5400.502
Tumor size (≥5 <5)1.8470.847–4.5780.126
Regional lymph nodes (yes no)5.8681.546–22.2720.009
Nerve invasion (yes no)9.7112.403–39.2430.001
Adjuvant chemotherapy (yes no)4.1282.226–10.1530.079
TCN11.5610.941–3.0020.073
CRC – colorectal cancer; CEA – carcinoembryonic antigen; CA125 – cancer antigen 125; CA19-19 – cancer antigen 19-9.

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Medical Science Monitor eISSN: 1643-3750
Medical Science Monitor eISSN: 1643-3750