28 August 2020>: Clinical Research
Circ_cse1l Inhibits Colorectal Cancer Proliferation by Binding to eIF4A3
Bin Xu 1ABCDEF , Ning Yang 1BCDF , Yabin Liu 1BCDF , Peng Kong 2ACE , Mei Han 2AG , Binghui Li 1ABCDEFG*DOI: 10.12659/MSM.923876
Med Sci Monit 2020; 26:e923876
Table 1 Correlation between the expression of circ_cse1l and the clinicopathology of colorectal cancer patients.
Clinical parameter | Group | No. of patients | Mean±S.E. | t-value | P-value |
---|---|---|---|---|---|
Gender | Male | 27 | 5.033±2.190 | 0.74 | 0.466 |
Female | 23 | 5.582±2.952 | |||
Age (years) | ≤60 | 19 | 5.047±2.381 | 0.51 | 0.611 |
>60 | 31 | 5.432±2.685 | |||
Tumor size (cm) | ≤5 | 33 | 5.136±2.783 | 0.57 | 0.571 |
>5 | 17 | 5.576±2.094 | |||
Histology/differentiation | Well+Moderate | 41 | 5.363±2.637 | 0.45 | 0.652 |
Poor | 9 | 4.933±2.252 | |||
Depth of invasion | T1+T2 | 11 | 3.581±2.046 | 2.65 | 0.011* |
T3+T4 | 39 | 5.766±2.343 | |||
Lymph node metastasis | Negative | 35 | 5.485±2.797 | 0.98 | 0.332 |
Positive | 15 | 4.821±1.881 | |||
Tumor stage | I–II | 34 | 5.601±2.755 | 1.43 | 0.161 |
III–IV | 16 | 4.618±1.988 | |||
Tumor location | Colon | 23 | 4.826±2.357 | 1.19 | 0.239 |
Rectum | 27 | 5.677±2.696 | |||
* P |