Bioinformatics-Based Study to Investigate Potential Differentially Expressed Genes and miRNAs in Pediatric Sepsis

23 June 2020 : Database Analysis

Kexin Xie^1BE, Shan Kong^1CE, Fuxing Li^1DF, Yulin Zhang^1CD, Jing Wang^2DF, Weidong Zhao^1AG*

DOI: 10.12659/MSM.923881

Med Sci Monit 2020; 26:e923881

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Supplementary Table 1 GO biological process terms for DEGs between the control and pediatric sepsis groups.

Index	Name	P-value	Adjusted P-value	Odds ratio	Combined score
1	Neutrophil degranulation (GO: 0043312)	3.277e-51	1.672e-47	12.09	1405.58
2	Neutrophil activation involved in immune response (GO: 0002283)	5.617e-51	1.433e-47	11.99	1387.48
3	Neutrophil mediated immunity (GO: 0002446)	9.578e-51	1.629e-47	11.89	1369.74
4	Membrane raft assembly (GO: 0001765)	0.00002597	0.004734	45.25	477.76
5	Complement receptor mediated signaling pathway (GO: 0002430)	0.000002892	0.001342	36.20	461.67
6	Positive regulation of superoxide anion generation (GO: 0032930)	0.000004505	0.001642	32.91	405.11
7	Immunoglobulin mediated immune response (GO: 0016064)	0.00007155	0.01074	33.94	323.93
8	B cell mediated immunity (GO: 0019724)	0.00007155	0.01106	33.94	323.93
9	Regulation of superoxide anion generation (GO: 0032928)	0.000009593	0.002577	27.85	321.74
10	Immune response-activating cell surface receptor signaling pathway (GO: 0002429)	0.000002132	0.001209	22.62	295.44

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