23 June 2020>: Database Analysis
Bioinformatics-Based Study to Investigate Potential Differentially Expressed Genes and miRNAs in Pediatric Sepsis
Kexin Xie 1BE* , Shan Kong 1CE* , Fuxing Li 1DF , Yulin Zhang 1CD , Jing Wang 2DF , Weidong Zhao 1AG*DOI: 10.12659/MSM.923881
Med Sci Monit 2020; 26:e923881
Supplementary Table 2 GO molecular function terms for DEGs between the control and pediatric sepsis groups.
Index | Name | P-value | Adjusted P-value | Odds ratio | Combined score |
---|---|---|---|---|---|
1 | Complement receptor activity (GO: 0004875) | 0.000004505 | 0.005186 | 32.91 | 405.11 |
2 | Phosphofructokinase activity (GO: 0008443) | 0.002461 | 0.3147 | 25.86 | 155.33 |
3 | Interleukin-1 receptor binding (GO: 0005149) | 0.0005490 | 0.1580 | 18.10 | 135.88 |
4 | C-C chemokine binding (GO: 0019957) | 0.003257 | 0.3124 | 22.62 | 129.57 |
5 | UDP-glucosyltransferase activity (GO: 0035251) | 0.004158 | 0.3190 | 20.11 | 110.26 |
6 | Hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines (GO: 0016813) | 0.005159 | 0.3493 | 18.10 | 95.33 |
7 | Protein kinase C activity (GO: 0004697) | 0.005159 | 0.3712 | 18.10 | 95.33 |
8 | Metalloendopeptidase inhibitor activity (GO: 0008191) | 0.007458 | 0.4518 | 15.08 | 73.88 |
9 | Cysteine-type endopeptidase inhibitor activity (GO: 0004869) | 0.0002446 | 0.09383 | 8.87 | 73.78 |
10 | Cysteine-type endopeptidase inhibitor activity involved in apoptotic process (GO: 0043027) | 0.002270 | 0.3265 | 11.31 | 68.87 |