03 August 2020: Review Articles
Galectins for Diagnosis and Prognostic Assessment of Human Diseases: An Overview of Meta-Analyses
Yiting Liu 12ABCDEF* , Hao Meng 13ABCDEF* , Shixue Xu 1ABCDEF* , Xingshun Qi 1ABCDEF*DOI: 10.12659/MSM.923901
Med Sci Monit 2020; 26:e923901
Table 3 Evidence from meta-analyses regarding clinical use of galectins in pregnancy.
| First author | Journal (Year) | Regions | No. studies (Pts.) | Galectins studied | Diseases studied | Outcomes of interests | Effect sizes | Conclusions |
|---|---|---|---|---|---|---|---|---|
| Wu P | Int J Mol Sci (2015) | UK Hartshill | 9 (NA) | Galectin-13 | Preeclampsia | Diagnosis | Area under the curve Diagnostic odds ratio Sensitivity Specificity | Galectin-13 has a diagnostic value for preeclampsia |
| Zhong Y | BMC Pregnancy Childbirth (2015) | China Hunan | 13 (60786) | Galectin-13 | Early preeclampsia Preeclampsia Small for gestational age Preterm delivery | Diagnosis | Sensitivity Specificity | Galectin-13 has a diagnostic value for early preeclampsia, preeclampsia, small for gestational age, and preterm delivery |
| Zhu X | Ann Med (2015) | China Shanghai | 4 (NA) | Galectin-13 | All preeclampsia Early preeclampsia Late preeclampsia | Diagnosis | Sensitivity | Galectin-13 combined with uterine artery pulsatility index exhibits a relatively good predictive ability for early preeclampsia, but a poor predictive ability for late preeclampsia |
| NA – not available. | ||||||||