Galectins for Diagnosis and Prognostic Assessment of Human Diseases:
An Overview of Meta-Analyses

03 August 2020 : Review article

Yiting Liu^12ABCDEF, Hao Meng^13ABCDEF, Shixue Xu^1ABCDEF, Xingshun Qi^1ABCDEF*

DOI: 10.12659/MSM.923901

Med Sci Monit 2020; 26:e923901

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Table 3 Evidence from meta-analyses regarding clinical use of galectins in pregnancy.

First author	Journal (Year)	Regions	No. studies (Pts.)	Galectins studied	Diseases studied	Outcomes of interests	Effect sizes	Conclusions
Wu P	Int J Mol Sci (2015)	UK Hartshill	9 (NA)	Galectin-13	Preeclampsia	Diagnosis	Area under the curve Diagnostic odds ratio Sensitivity Specificity	Galectin-13 has a diagnostic value for preeclampsia
Zhong Y	BMC Pregnancy Childbirth (2015)	China Hunan	13 (60786)	Galectin-13	Early preeclampsia Preeclampsia Small for gestational age Preterm delivery	Diagnosis	Sensitivity Specificity	Galectin-13 has a diagnostic value for early preeclampsia, preeclampsia, small for gestational age, and preterm delivery
Zhu X	Ann Med (2015)	China Shanghai	4 (NA)	Galectin-13	All preeclampsia Early preeclampsia Late preeclampsia	Diagnosis	Sensitivity	Galectin-13 combined with uterine artery pulsatility index exhibits a relatively good predictive ability for early preeclampsia, but a poor predictive ability for late preeclampsia
NA – not available.

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