19 August 2020 : Database Analysis
A Predictive Nomogram for Early Mortality in Stage IV Gastric Cancer
Yuqian Feng1ACDE, Kaibo Guo1ABDE, Huimin Jin1BC, Yuying Xiang1D, Yiting Zhang1E, Shanming Ruan2AFG*DOI: 10.12659/MSM.923931
Med Sci Monit 2020; 26:e923931
Table 2 Multivariable logistic regression for analyzing the risk factors for early death.
| Factors | Total early death | Cancer-specific early death | Non-cancer-specific early death | |||
|---|---|---|---|---|---|---|
| OR (95% CI) | P-value | OR (95% CI) | P-value | OR(95% CI) | P-value | |
| ≤55 | Ref | 1 | Ref | 1 | Ref | 1 |
| 56–65 | 0.853 (0.436–1.582) | 0.582 | 0.931 (0.551–1.575) | 0.787 | 1.879 (1.208–2.979) | 0.17 |
| 66–75 | 3.252 (1.827–5.899) | <0.001 | 1.050 (0.607–1.828) | 0.863 | 2.729 (1.785–4.273) | <0.001 |
| ≥76 | 3.441 (1.927–6.265) | <0.001 | 1.333 (0.747–2.410) | 0.335 | 3.258 (2.154–5.059) | <0.001 |
| White | Ref | 1 | Ref | 1 | Ref | 1 |
| Black | 1.081 (0.600–1.909) | 0.792 | NS | NS | NS | NS |
| Asian or Pacific Islander | 0.615 (0.356–1.033) | 0.073 | NS | NS | NS | NS |
| American Indian/Alaska Native | 1.886 (0.116–25.241) | 0.632 | NS | NS | NS | NS |
| Unknown | NA | NA | NA | NA | NA | NA |
| Female | Ref | 1 | 1 | 1 | Ref | 1 |
| Male | NS | NS | NS | NS | NS | NS |
| Unmarried | Ref | 1 | Ref | 1 | Ref | 1 |
| Married | 0.724 (0.474–1.108) | 0.136 | 1.007 (0.664–1.518) | 0.972 | 0.754 (0.577–0.987) | 0.13 |
| Unknown | NA | NA | NA | NA | NA | NA |
| Uninsured | Ref | 1 | Ref | 1 | Ref | 1 |
| Insured | 1.719 (0.624–6.101) | 0.34 | NS | NS | NS | NS |
| Unknown | NA | NA | NA | NA | NA | NA |
| Non-cardia | Ref | 1 | Ref | 1 | Ref | 1 |
| Cardia | 0.307 (0.138–0.627) | 0.002 | NS | NS | NS | NS |
| Unknown | NA | NA | NA | NA | NA | NA |
| Adenocarcinoma(exclude signet ring cell) | Ref | 1 | Ref | 1 | Ref | 1 |
| Signet ring cell | NS | NS | 1.023 (0.616–1.715) | 0.93 | NS | NS |
| Others | NA | NA | NA | NA | NA | NA |
| <3 | Ref | 1 | Ref | 1 | Ref | 1 |
| ≥3 <5 | 0.850 (0.392–1.902) | 0.685 | 1.456 (0.765–2.749) | 0.248 | NS | NS |
| ≥5 <7 | 0.693 (0.318–1.558) | 0.364 | 1.435 (0.741–2.754) | 0.28 | NS | NS |
| ≥7 <9 | 1.104 (0.484–2.583) | 0.817 | 1.842 (0.895–3.809) | 0.097 | NS | NS |
| ≥9 | 0.916 (0.401–2.145) | 0.836 | 2.414 (1.114–5.333) | 0.027 | NS | NS |
| Unknown | NA | NA | NA | NA | NA | NA |
| T1 | Ref | 1 | Ref | 1 | Ref | 1 |
| T2 | 0.395 (0.073–1.713) | 0.237 | 0.968 (0.338–2.775) | 0.952 | 0.443 (0.169–0.966) | 0.113 |
| T3 | 1.076 (0.405–3.062) | 0.886 | 1.698 (0.713–4.002) | 0.226 | 0.581 (0.346–0.949) | 0.076 |
| T4 | 1.726 (0.656–4.882) | 0.283 | 2.287 (0.951–5.440) | 0.061 | 0.693 (0.455–1.052) | 0.155 |
| Others | NA | NA | NA | NA | NA | NA |
| N0 | Ref | 1 | Ref | 1 | Ref | 1 |
| N1 | 0.711 (0.349–1.448) | 0.345 | 0.991 (0.531–1.834) | 0.977 | NS | NS |
| N2 | 0.649 (0.312–1.351) | 0.246 | 1.587 (0.822–3.061) | 0.167 | NS | NS |
| N3 | 0.819 (0.427–1.600) | 0.552 | 1.524 (0.820–2.796) | 0.177 | NS | NS |
| Others | NA | NA | NA | NA | NA | NA |
| I | Ref | 1 | Ref | 1 | Ref | 1 |
| II | 3.591 (0.586–70.424) | 0.25 | 2.339 (0.689–8.178) | 0.171 | NS | NS |
| III | 6.768 (1.149–131.038) | 0.082 | 3.363 (1.011–11.525) | 0.047 | NS | NS |
| IV | 11.195 (1.438–240.700) | 0.044 | 7.594 (1.302–64.796) | 0.035 | NS | NS |
| Others | NA | NA | NA | NA | NA | NA |
| Yes | Ref | 1 | Ref | 1 | Ref | 1 |
| No | 0.447 (0.285–0.699) | <0.001 | 0.564 (0.346–0.903) | 0.019 | 0.822 (0.626–1.078) | 0.667 |
| Others | NA | NA | NA | NA | NA | NA |
| Yes | Ref | 1 | Ref | 1 | Ref | 1 |
| No | 0.223 (0.102–0.485) | <0.001 | 0.642 (0.255–1.457) | 0.314 | 0.723 (0.526–1.014) | 0.027 |
| Others | NA | NA | NA | NA | NA | NA |
| Bone metastases | ||||||
| Yes | Ref | 1 | Ref | 1 | Ref | 1 |
| No | 0.813 (0.296–2.525) | 0.701 | 0.640 (0.178–1.800) | 0.438 | NS | NS |
| Others | NA | NA | NA | NA | NA | NA |
| Yes | Ref | 1 | Ref | 1 | Ref | 1 |
| No | 0.125 (0.018–1.282) | 0.051 | NS | NS | NS | NS |
| Others | NA | NA | NA | NA | NA | NA |
| Yes | Ref | 1 | Ref | 1 | Ref | 1 |
| No | 2.835 (1.005–7.888) | 0.045 | 11.912 (2.338–218.646) | 0.018 | NS | NS |
| Unknown | NA | NA | NA | NA | NA | NA |
| Ref – reference; OR – odds ratio; NA – not available; NS – not significant. | ||||||