02 August 2020: Review Articles
The Potential Protective Role of Aspirin Against Migraine in Pregnant Women
Xijing Liu 12AEF , Yunhui Gong 12AG*DOI: 10.12659/MSM.923959
Med Sci Monit 2020; 26:e923959
Table 1 Studies examining the relation between migraine and preeclampsia or pregnancy-induced hypertension.
| Author (year) | Study type | Population (N) | Main results |
|---|---|---|---|
| Rotton WN (1959) []14 | Cross-sectional | 221 | 21.4% of migraine pregnancies developed PE |
| Bushnell CD (2009) []15 | Case-control | 33,956 migraine, 18,311,582 controls | OR 2.3 (95% CI 2.1 to 2.5) for PIH/PE |
| Chen HM (2010) []16 | Case-control | 4,911 migraine, 24,555 controls | Adjusted OR 1.34 (95% CI 1.02 to 1.77) for PE |
| Facchinetti F (2009) []9 | Prospective cohort | 270 migraine, 432 controls | Adjusted OR 2.85 (95% CI 1.40 to 5.81) for PIH |
| Michelle AW (2011) []17 | Prospective cohort | 586 migraine, 2,787 controls | OR 1.53 (95% CI 1.09 to 2.16) for PE |
| Grossman TB (2017) []18 | Retrospective observation | 86 | 21.3% severe migraine developed PE |
| PIH – pregnancy-induced hypertension; PE – preeclampsia; OR – odds ratio. | |||