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02 August 2020: Review Articles

The Potential Protective Role of Aspirin Against Migraine in Pregnant Women

Xijing Liu 12AEF , Yunhui Gong 12AG*

DOI: 10.12659/MSM.923959

Med Sci Monit 2020; 26:e923959

Table 1 Studies examining the relation between migraine and preeclampsia or pregnancy-induced hypertension.

Author (year)Study typePopulation (N)Main results
Rotton WN (1959) []14 Cross-sectional22121.4% of migraine pregnancies developed PE
Bushnell CD (2009) []15 Case-control33,956 migraine, 18,311,582 controlsOR 2.3 (95% CI 2.1 to 2.5) for PIH/PE
Chen HM (2010) []16 Case-control4,911 migraine, 24,555 controlsAdjusted OR 1.34 (95% CI 1.02 to 1.77) for PE
Facchinetti F (2009) []9 Prospective cohort270 migraine, 432 controlsAdjusted OR 2.85 (95% CI 1.40 to 5.81) for PIH
Michelle AW (2011) []17 Prospective cohort586 migraine, 2,787 controlsOR 1.53 (95% CI 1.09 to 2.16) for PE
Grossman TB (2017) []18 Retrospective observation8621.3% severe migraine developed PE
PIH – pregnancy-induced hypertension; PE – preeclampsia; OR – odds ratio.

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Medical Science Monitor eISSN: 1643-3750
Medical Science Monitor eISSN: 1643-3750