19 July 2020 : Database Analysis
Systematic Profiling of Alternative Splicing for Sarcoma Patients Reveals Novel Prognostic Biomarkers Associated with Tumor Microenvironment and Immune Cells
Chuan Hu1ABCEF*, Yuanhe Wang1ABC, Chuan Liu2DEF, Rui Shen1DE, Bo Chen3F, Kang Sun1B, Huili Rao4C, Lin Ye3E, Jianjun Ye3C, Shaoqi Tian1ABCDEFDOI: 10.12659/MSM.924126
Med Sci Monit 2020; 26:e924126
Table 2 Multivariate COX analysis of disease-free survival-related AS events.
| Symbol | AS type | HR | Lower.95 | Upper.95 | P value |
|---|---|---|---|---|---|
| SPIDR | ES | 0.000367 | 1.37E-06 | 0.09814 | 0.005537 |
| MMP19 | ES | 0.003436 | 2.96E-05 | 0.398999 | 0.019351 |
| PTCH2 | AT | 18.55505 | 1.876145 | 183.5092 | 0.012485 |
| BEST3 | AT | 8.490379 | 1.244015 | 57.94666 | 0.029052 |
| SLC27A1 | ES | 0.015654 | 0.001242 | 0.197346 | 0.001304 |
| IRAK1 | ES | 1.99E-05 | 4.86E-08 | 0.008167 | 0.000421 |
| ZNF331 | AP | 3.224539 | 1.09384 | 9.505643 | 0.03379 |
| PPRC1 | ES | 418.7191 | 7.698737 | 22773.3 | 0.003066 |
| AS – alternative splicing; ES – exon skip; AP – alternate promoter; AT – alternate terminator. | |||||