22 October 2020 : Clinical Research
Embryological Characteristics and Clinical Outcomes of Oocytes with Heterogeneous Zona Pellucida During Assisted Reproduction Treatment: A Retrospective Study
Chengshuang Pan1BCEF, Huan Zhang1ADF*DOI: 10.12659/MSM.924316
Med Sci Monit 2020; 26:e924316
Table 2 Embryological and clinical outcomes for patients in both ICSI and IVF cycles.
| Parameter | ICSI cycles | IVF cycles | ||||
|---|---|---|---|---|---|---|
| HZP | Normal | P value | HZP | Normal | P value | |
| Total cycles (n) | 46 | 206 | 29 | 521 | ||
| Retrieved oocytes (mean±SD) | 9.4±6.2 | 10.9±7.5 | 0.152 | 8.8±5.1 | 11.1±6.6 | 0.071 |
| MII oocyte rate (%) | 62.40% | 83.50% | <0.001 | 62.90% | 90.40% | <0.001 |
| Normal fertilization rate (%) | 77.70% | 74.20% | 0.221 | 20.30% | 66.10% | <0.001 |
| Cleavage rate (%) | 95.70% | 94.10% | 0.355 | 76.90% | 95.50% | <0.001 |
| High quality embryo rate (%) | 23.00% | 31.20% | 0.019 | 35.00% | 30.10% | 0.505 |
| Available embryos for transfer (mean±SD) | 4.4±4.4 | 6.3±5.2 | 0.016 | 1.4±2.5 | 7.0±4.6 | <0.001 |
| Abandoned transfer rate (%) | 21.70% | 21.80% | 0.988 | 58.60% | 15.20% | <0.001 |
| Transferred cycles (n) | 36 | 161 | 12 | 442 | ||
| Transferred embryos (mean±SD) | 2.1±0.6 | 2.2±0.6 | 0.299 | 1.8±0.7 | 2.2±0.5 | 0.016 |
| Positive HCG rate (%) | 47.20% | 49.70% | 0.789 | 50.00% | 53.20% | 0.828 |
| Implantation rate (%) | 24.00% | 24.90% | 0.876 | 22.70% | 27.90% | 0.590 |
| Pregnancy rate (%) | 38.90% | 44.10% | 0.568 | 41.70% | 46.40% | 0.747 |
| Miscarriage rate (%) | 21.40% | 12.70% | 0.390 | 20.0% | 11.70% | 0.572 |
| ICSI – intracytoplasmic sperm injection; IVF – fertilization; HZP – heterogeneous zona pellucida; SD – standard deviation; HCG – human chorionic gonadotropin. | ||||||